(2R,3R,4R,5R)-5-((benzoyloxy)Methyl)-3-Methyl-2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate

Base Information

Chemical Name:(2R,3R,4R,5R)-5-((benzoyloxy)Methyl)-3-Methyl-2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate
CAS No.:957535-53-4
Molecular Formula:C32H28N2O9
Molecular Weight:584.582
Hs Code.:
Mol file:957535-53-4.mol

Synonyms:(2R,3R,4R,5R)-5-((benzoyloxy)Methyl)-3-Methyl-2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate;2',3',5'-Tri-O-benzoyl-2'-C-Methyl-5-Methyluridine;5-Methyl-2'-C-methyluridine 2',3',5'-tribenzoate

Suppliers and Price of (2R,3R,4R,5R)-5-((benzoyloxy)Methyl)-3-Methyl-2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 7 raw suppliers

Chemical Property of (2R,3R,4R,5R)-5-((benzoyloxy)Methyl)-3-Methyl-2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3R,4R,5R)-5-((benzoyloxy)Methyl)-3-Methyl-2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate

There total 4 articles about (2R,3R,4R,5R)-5-((benzoyloxy)Methyl)-3-Methyl-2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 15397-15-6,15397-16-7,30361-19-4
1,2,3,5-Tetra-O-benzoyl-2-C-methyl-α(β)-D-ribofuranose

: 65-71-4,28806-14-6,691841-57-3
thymin

: 957535-53-4
C₃₂H₂₈N₂O₉

Guidance literature:: With tin(IV) chloride; bis-(trimethylsilyl)acetamide; In acetonitrile; for 3h; Heating;
DOI:10.1080/07328319708006205

Reference yield: 85.0%

: 65-71-4,28806-14-6,691841-57-3
thymin

: (2S/R,3R,4R,5R)-5-((benzoyloxy)methyl)-3-methyltetrahydrofuran-2,3,4-triyltribenzoate

: 957535-53-4
C₃₂H₂₈N₂O₉

Guidance literature:: thymin; With N,O-bis-(trimethylsilyl)-acetamide; In acetonitrile; for 2h; Reflux;

(2S/R,3R,4R,5R)-5-((benzoyloxy)methyl)-3-methyltetrahydrofuran-2,3,4-triyltribenzoate; With tin(IV) chloride; In acetonitrile; at 100 ℃; for 5h;

With sodium hydrogencarbonate; at 0 ℃;

Reference yield:

: 98-88-4
benzoyl chloride

: 957535-53-4
C₃₂H₂₈N₂O₉

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) CeCl₃, 2.) DMAP, Et₃N

2: 94 percent / bis(trimethylsilyl)acetamide, SnCl₄ / acetonitrile / 3 h / Heating

With dmap; cerium(III) chloride; tin(IV) chloride; bis-(trimethylsilyl)acetamide; triethylamine; In acetonitrile;
DOI:10.1080/07328319708006205