4-Isoxazolecarboxylic acid, 5-cyclopropyl-3-phenyl-

Base Information

Chemical Name:4-Isoxazolecarboxylic acid, 5-cyclopropyl-3-phenyl-
CAS No.:943130-42-5
Molecular Formula:C13H11NO3
Molecular Weight:229.235
Hs Code.:
Mol file:943130-42-5.mol

Synonyms:4-Isoxazolecarboxylic acid, 5-cyclopropyl-3-phenyl-

Suppliers and Price of 4-Isoxazolecarboxylic acid, 5-cyclopropyl-3-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-CYCLOPROPYL-3-PHENYLISOXAZOLE-4-CARBOXYLIC ACID 95.00%
5MG
$ 505.90

Total 2 raw suppliers

Chemical Property of 4-Isoxazolecarboxylic acid, 5-cyclopropyl-3-phenyl-

Chemical Property:

PSA：63.33000
LogP:2.91720

Purity/Quality:

99% ^*data from raw suppliers

5-CYCLOPROPYL-3-PHENYLISOXAZOLE-4-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-Isoxazolecarboxylic acid, 5-cyclopropyl-3-phenyl-

There total 4 articles about 4-Isoxazolecarboxylic acid, 5-cyclopropyl-3-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 943130-41-4
ethyl 5-cyclopropyl-3-phenyl-1,2-oxazole-4-carboxylate

: 943130-42-5
5-cyclopropyl-3-phenyl-1,2-oxazole-4-carboxylic acid

Guidance literature:: ethyl 5-cyclopropyl-3-phenyl-1,2-oxazole-4-carboxylate; With sodium hydroxide; water; In ethanol; at 80 ℃; for 3h;

With hydrogenchloride; In water; pH=1;

Reference yield:

: 100-52-7
benzaldehyde

: 943130-42-5
5-cyclopropyl-3-phenyl-1,2-oxazole-4-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: sodium carbonate; hydroxylamine hydrochloride / water; ethanol / 2 h / 0 - 20 °C

2: N-chloro-succinimide / N,N-dimethyl-formamide / 0 - 20 °C

3: triethylamine / dichloromethane / 20 °C

4: lithium hydroxide monohydrate; water / ethanol / 50 °C

With N-chloro-succinimide; lithium hydroxide monohydrate; hydroxylamine hydrochloride; water; sodium carbonate; triethylamine; In ethanol; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

: 932-90-1
Benzaldoxime

: 943130-42-5
5-cyclopropyl-3-phenyl-1,2-oxazole-4-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: N-chloro-succinimide / N,N-dimethyl-formamide / 0 - 20 °C

2: triethylamine / dichloromethane / 20 °C

3: lithium hydroxide monohydrate; water / ethanol / 50 °C

With N-chloro-succinimide; lithium hydroxide monohydrate; water; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide;