3,6-Dioxo-5β-24-cholanoic acid methyl ester

Base Information

• Chemical Name: 3,6-Dioxo-5β-24-cholanoic acid methyl ester
• CAS No.: 1175-04-8
• Molecular Formula: C25H38O4
• Molecular Weight: 402.574
• Mol file: 1175-04-8.mol

Synonyms:3,6-Dioxo-5β-24-cholanoic acid methyl ester;3,6-Dioxo-5β-cholan-24-oic acid methyl ester

Chemical Property of 3,6-Dioxo-5β-24-cholanoic acid methyl ester

Chemical Property:

• PSA: 60.44000
• LogP: 4.98270

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,6-Dioxo-5β-24-cholanoic acid methyl ester

There total 14 articles about 3,6-Dioxo-5β-24-cholanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

methyl hyodeoxycholate (2868-48-6) → 3,6-diketo-5β-cholan-24-oic acid methyl ester (1175-04-8)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; for 8h; Ambient temperature;

DOI:10.1016/S0039-128X(96)00114-6

Reference yield: 78.0%

methyl hyodeoxycholate (2868-48-6) → 3α-oxo-6α-hydroxy-5β-cholan-24-oic acid methyl ester (3360-89-2) + 3,6-diketo-5β-cholan-24-oic acid methyl ester (1175-04-8)

Guidance literature:

With dimethoxydioxirane*H₂O; In acetone; at 0 - 5 ℃; for 16h;

DOI:10.1016/S0040-4039(99)00834-5

Reference yield: 77.0%

3α-ol-6-oxo-5β-24-cholanoic acid methyl ester (2862-62-6) → 3,6-diketo-5β-cholan-24-oic acid methyl ester (1175-04-8)

Guidance literature:

With perfluoro-cis-2-n-butyl-3-n-propyloxaziridine; In various solvent(s); Ambient temperature;

DOI:10.1016/S0040-4039(00)60884-5

upstream raw materials:

diazomethane

3,6-dioxocholanoic acid

methyl hyodeoxycholate

3α-ol-6-oxo-5β-24-cholanoic acid methyl ester

Downstream raw materials:

C₃₉H₅₀Cl₂N₆O₂S₂

C₃₉H₅₀F₂N₆O₂S₂

C₃₉H₅₀Br₂N₆O₂S₂

C₄₁H₅₆N₆O₄S₂