3-Hydroxy-3-methylglutaric-d3 Anhydride

Base Information

Chemical Name:3-Hydroxy-3-methylglutaric-d3 Anhydride
CAS No.:115135-38-1
Molecular Formula:C₆H₈O₄
Molecular Weight:147.103
Hs Code.:
DSSTox Substance ID:DTXSID10473680
Wikidata:Q82303261
Mol file:115135-38-1.mol

Synonyms:3-Hydroxy-3-methylglutaric-d3 Anhydride;115135-38-1;4-hydroxy-4-(trideuteriomethyl)oxane-2,6-dione;Dicrotalic-d3 Anhydride;DTXSID10473680

Suppliers and Price of 3-Hydroxy-3-methylglutaric-d3 Anhydride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
3-Hydroxy-3-methylglutaric-d3 Anhydride
10mg
$ 425.00

TRC
3-Hydroxy-3-methylglutaric-d3Anhydride
10mg
$ 140.00

Total 3 raw suppliers

Chemical Property of 3-Hydroxy-3-methylglutaric-d3 Anhydride

Chemical Property:

PSA：63.60000
LogP:-0.39900
Solubility.:Acetone
XLogP3:-0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:147.06108897
Heavy Atom Count:10
Complexity:168

Purity/Quality:

95% ^*data from raw suppliers

3-Hydroxy-3-methylglutaric-d3 Anhydride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC(=O)OC(=O)C1)O
Isomeric SMILES:[2H]C([2H])([2H])C1(CC(=O)OC(=O)C1)O
Uses A 3-Alkyl-3-hydroxyglutaric acid; a new class of hypocholesterolemic HMG CoA reductase inhibitors.

Technology Process of 3-Hydroxy-3-methylglutaric-d3 Anhydride

There total 2 articles about 3-Hydroxy-3-methylglutaric-d3 Anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 59060-36-5
3-hydroxy-3-<²H3>methylglutaric acid

: 115135-38-1
3-hydroxy-3-pentane-1,5-dioic anhydride

Guidance literature:: With acetic anhydride; for 18h;

Reference yield:

: 59060-35-4
4-hydroxy-4-<²H3>methylhepta-1,6-diene

: 115135-38-1
3-hydroxy-3-pentane-1,5-dioic anhydride

Guidance literature:: Multi-step reaction with 2 steps

1: 1) O₃-O₂; 2) 30percent aq. H₂O₂, H₂SO₄ / 1) ethyl acetate, -78 deg C; 2) H₂O, 2 h, reflux

2: 76 percent / acetic anhydride / 18 h

With sulfuric acid; dihydrogen peroxide; oxygen; acetic anhydride; ozone;