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Encyclopedia

Vadadustat

Base Information Edit
Vadadustat

Synonyms:Vadadustat

Suppliers and Price of Vadadustat
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Vadadustat
  • 5mg
  • $ 195.00
  • DC Chemicals
  • Vadadustat >98%
  • 250 mg
  • $ 1000.00
  • DC Chemicals
  • Vadadustat >98%
  • 1 g
  • $ 1900.00
  • Crysdot
  • Vadadustat(AKB-6548/PG-1016548) 97%
  • 50mg
  • $ 1015.00
  • Crysdot
  • Vadadustat(AKB-6548/PG-1016548) 97%
  • 10mg
  • $ 339.00
  • Crysdot
  • Vadadustat(AKB-6548/PG-1016548) 97%
  • 25mg
  • $ 597.00
  • ChemScene
  • Vadadustat 99.25%
  • 50mg
  • $ 490.00
  • ChemScene
  • Vadadustat 99.25%
  • 5mg
  • $ 120.00
  • ChemScene
  • Vadadustat 99.25%
  • 10mg
  • $ 190.00
  • ChemScene
  • Vadadustat 99.25%
  • 2mg
  • $ 70.00
Total 30 raw suppliers
Chemical Property of Vadadustat Edit
Chemical Property:
  • Boiling Point:674.6±55.0 °C(Predicted) 
  • PKA:4.09±0.40(Predicted) 
  • PSA:99.52000 
  • Density:1.461±0.06 g/cm3(Predicted) 
  • LogP:2.31290 
  • Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere 
  • Solubility.:DMSO (Slightly), Methanol (Slightly) 
Purity/Quality:

99% *data from raw suppliers

Vadadustat *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Description Vadadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) and HIF-PH3 (IC50s = 1.1 and 0.39 micromolar, respectively). It stabilizes HIF-1α in mouse hepatocyte nuclear extracts. Vadadustat (50 and 100 mg/kg) increases erythropoietin levels in mouse serum.
  • Uses Vadadustat is a novel HIF (Hypoxia-inducible factor) stabilizer. It provides an effective anemia treatment in nondialysis-dependent chronic kidney disease.
Technology Process of Vadadustat

There total 31 articles about Vadadustat which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With water; potassium hydroxide; In 2-methyltetrahydrofuran; at 20 - 30 ℃; for 3h; Inert atmosphere;
Guidance literature:
With hydrogen bromide; at 95 ℃; for 28h; Green chemistry;
Guidance literature:
With sodium ethanolate; In methanol; at 75 ℃; Reagent/catalyst; Inert atmosphere;
Refernces Edit
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