[4-(4-Chloro-phenyl)-2-methyl-thiazol-5-yl]-acetic acid

Base Information

Chemical Name:[4-(4-Chloro-phenyl)-2-methyl-thiazol-5-yl]-acetic acid
CAS No.:553630-41-4
Molecular Formula:C₁₂H₁₀ClNO₂S
Molecular Weight:267.736
Hs Code.:2934100090
DSSTox Substance ID:DTXSID30390204
Wikidata:Q82186698
ChEMBL ID:CHEMBL592460
Mol file:553630-41-4.mol

Synonyms:[4-(4-Chloro-phenyl)-2-methyl-thiazol-5-yl]-acetic acid;553630-41-4;2-[4-(4-chlorophenyl)-2-methyl-1,3-thiazol-5-yl]acetic acid;2-(4-(4-chlorophenyl)-2-methylthiazol-5-yl)acetic acid;CHEMBL592460;SCHEMBL5820072;DTXSID30390204;BDBM50309299;AKOS000303006;2-(4-(4-chlorophenyl)-2-methylthiazol-5-yl)aceticacid

Suppliers and Price of [4-(4-Chloro-phenyl)-2-methyl-thiazol-5-yl]-acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
[4-(4-Chloro-phenyl)-2-methyl-thiazol-5-yl]-acetic acid
1g
$ 378.00

Crysdot
2-(4-(4-Chlorophenyl)-2-methylthiazol-5-yl)aceticacid 97%
5g
$ 874.00

American Custom Chemicals Corporation
[4-(4-CHLORO-PHENYL)-2-METHYL-THIAZOL-5-YL]-ACETIC ACID 95.00%
1G
$ 672.00

AK Scientific
[4-(4-Chloro-phenyl)-2-methyl-thiazol-5-yl]-aceticacid
1g
$ 560.00

Total 3 raw suppliers

Chemical Property of [4-(4-Chloro-phenyl)-2-methyl-thiazol-5-yl]-acetic acid

Chemical Property:

Boiling Point:461.8±40.0 °C(Predicted)
PKA:3.99±0.10(Predicted)
PSA：78.43000
Density:1.386±0.06 g/cm3(Predicted)
LogP:3.39900
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:267.0120774
Heavy Atom Count:17
Complexity:282

Purity/Quality:

98%min ^*data from raw suppliers

[4-(4-Chloro-phenyl)-2-methyl-thiazol-5-yl]-acetic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=C(S1)CC(=O)O)C2=CC=C(C=C2)Cl

Technology Process of [4-(4-Chloro-phenyl)-2-methyl-thiazol-5-yl]-acetic acid

There total 3 articles about [4-(4-Chloro-phenyl)-2-methyl-thiazol-5-yl]-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62-55-5
thioacetamide

: 35158-39-5
3-bromo-3-(4-chlorobenzoyl)propionic acid

: 553630-41-4
[4-(4-chloro-phenyl)-2-methyl-thiazol-5-yl]-acetic acid

Guidance literature:: With isopropyl alcohol;
DOI:10.1039/jr9450000455

Reference yield:

: 3984-34-7
4-(4-chlorophenyl)-4-oxobutanoic acid

: 553630-41-4
[4-(4-chloro-phenyl)-2-methyl-thiazol-5-yl]-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: chloroform; bromine

2: isopropyl alcohol

With chloroform; bromine; isopropyl alcohol;
DOI:10.1039/jr9450000455