Chemical Property of Thioacetamide
Chemical Property:
- Appearance/Colour:white solid
- Vapor Pressure:22.5mmHg at 25°C
- Melting Point:108-112 °C(lit.)
- Refractive Index:1.543
- Boiling Point:111.7 °C at 760 mmHg
- PKA:13.25±0.29(Predicted)
- Flash Point:21.4 °C
- PSA：58.11000
- Density:1.07 g/cm3
- LogP:0.99270
- Storage Temp.:Store at RT.
- Solubility.:passes test2%
- Water Solubility.:16.3 g/100 mL (25 ºC)
- XLogP3:-0.3
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:1
- Rotatable Bond Count:0
- Exact Mass:75.01427034
- Heavy Atom Count:4
- Complexity:33
- Purity/Quality:
-
99% *data from raw suppliers
Thioacetamide *data from reagent suppliers
Safty Information:
- Pictogram(s):
T
- Hazard Codes:T
- Statements:
45-22-36/38-52/53
- Safety Statements:
53-45-61-99
- MSDS Files:
-
SDS file from LookChem
Useful:
- Chemical Classes:Other Classes -> Sulfur Compounds
- Canonical SMILES:CC(=S)N
- Inhalation Risk:Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.
- Effects of Long Term Exposure:The substance may have effects on the liver. This may result in tissue lesions. This substance is possibly carcinogenic to humans.
-
Uses
1. It can be used for the production of catalysts, stabilizers, polymerization inhibitors, electroplating additives, photographic chemicals, pesticides, dyeing auxiliary and processing agents. It can be also used as polymer curing agents, crosslinking agents, rubber additives and pharmaceutical raw materials.
2. It can be also used as vulcanizing agent and crosslinking agent of polymer, rubber additives, pharmaceutical raw materials, etc.
3. It can be also used as analytical reagents. It is used as an intermediate in organicsynthesis. Sulfide generation Substitute for H2S in laboratory qualitative analyses. Thioacetamide is a carcinogen, a hepatotoxicant. Thioacetamide induces acute chronic liver injury through the activation of protein synthesis of RNA, DNA, and gamma-glutamyl transpeptitase. Thioacetamide has been used in the synthesis of [email?protected] nano-array core-shell structure.
-
Production method
Thioacetamide can be obtained by the reaction of acetonitrile with hydrogen sulfide, or acetamide with phosphorus pentasulfide.
-
Description
Thioacetamide (TAA) is not known to occur in nature. It is
prepared by heating ammonium acetate and aluminum sulfide.
