3'-METHOXY-BIPHENYL-2-CARBALDEHYDE

Base Information

• Chemical Name: 3'-METHOXY-BIPHENYL-2-CARBALDEHYDE
• CAS No.: 38491-36-0
• Molecular Formula: C14H12O2
• Molecular Weight: 212.248
• Hs Code.: 2913000090
• Mol file: 38491-36-0.mol

Synonyms:AKOS BAR-0188;3'-METHOXY[1,1'-BIPHENYL]-2-CARBALDEHYDE;3'-METHOXY[1,1'-BIPHENYL]-2-CARBOXALDEHYDE;3'-METHOXY-BIPHENYL-2-CARBALDEHYDE;3'-METHOXY-BIPHENYL-2-CARBOXALDEHYDE;2-(3-Methoxyphenyl)benzaldehyde

Chemical Property of 3'-METHOXY-BIPHENYL-2-CARBALDEHYDE

Chemical Property:

• Melting Point: 53 °C
• PSA: 26.30000
• LogP: 3.17470

Purity/Quality:

99% ^*data from raw suppliers

3'-Methoxy-[1,1'-biphenyl]-2-carboxaldehyde ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of 3'-METHOXY-BIPHENYL-2-CARBALDEHYDE

There total 22 articles about 3'-METHOXY-BIPHENYL-2-CARBALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-methoxyphenylboronic acid (10365-98-7,1107579-37-2) + ortho-bromobenzaldehyde (6630-33-7) → 3'-methoxy-[1,1′]-biphenyl-2-carbaldehyde (38491-36-0)

Guidance literature:

With potassium phosphate; palladium diacetate; In tetrahydrofuran; water; at 110 ℃; for 15h; Inert atmosphere; Schlenk technique;

DOI:10.1055/a-1404-4966

Reference yield: 90.0%

3-methoxyphenyl bromide (2398-37-0) + 2-formylbenzene boronic acid (40138-16-7) → 3'-methoxy-[1,1′]-biphenyl-2-carbaldehyde (38491-36-0)

Guidance literature:

With cesium fluoride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; Heating;

DOI:10.1021/jo025962y

Reference yield: 90.0%

2-iodobenzaldehyde (26260-02-6) + 3-methoxyphenylboronic acid (10365-98-7,1107579-37-2) → 3'-methoxy-[1,1′]-biphenyl-2-carbaldehyde (38491-36-0)

Guidance literature:

With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; water; for 24h; Heating;

DOI:10.1021/ol048668w

upstream raw materials:

2-iodobenzaldehyde

3-methoxyphenylboronic acid

3-methoxyphenyl bromide

2-formylbenzene boronic acid

Downstream raw materials:

1-(3'-methoxy-[1,1'-biphenyl]-2-yl)-3-phenylprop-2-yn-1-one

9-methoxyphenanthridine

7-methoxyphenanthridine