Ethyl 4-(2,4-dichlorophenyl)-1-methyl-1H-pyrrole-3-carboxylate

Base Information

Chemical Name:Ethyl 4-(2,4-dichlorophenyl)-1-methyl-1H-pyrrole-3-carboxylate
CAS No.:191668-16-3
Molecular Formula:C14H13Cl2NO2
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID90702304
Wikidata:Q82634180
Mol file:191668-16-3.mol

Synonyms:191668-16-3;DTXSID90702304;DCVXLBMFYNCAHY-UHFFFAOYSA-N;Ethyl 4-(2,4-dichlorophenyl)-1-methyl-1H-pyrrole-3-carboxylate

Suppliers and Price of Ethyl 4-(2,4-dichlorophenyl)-1-methyl-1H-pyrrole-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Ethyl 4-(2,4-dichlorophenyl)-1-methyl-1H-pyrrole-3-carboxylate

Chemical Property:

PSA：31.23000
LogP:4.17560
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:297.0323340
Heavy Atom Count:19
Complexity:327

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CN(C=C1C2=C(C=C(C=C2)Cl)Cl)C

Technology Process of Ethyl 4-(2,4-dichlorophenyl)-1-methyl-1H-pyrrole-3-carboxylate

There total 2 articles about Ethyl 4-(2,4-dichlorophenyl)-1-methyl-1H-pyrrole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 191668-09-4
4-(2,4-Dichloro-phenyl)-1H-pyrrole-3-carboxylic acid ethyl ester

: 74-88-4
methyl iodide

: 191668-16-3
4-(2,4-dichloro-phenyl)-1-methyl-1H-pyrrole-3-carboxylic acid ethyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 18h;

Reference yield:

: 1504-68-3,24393-62-2
(E)-ethyl 3-(2,4-dichlorophenyl)acrylate

: 191668-16-3
4-(2,4-dichloro-phenyl)-1-methyl-1H-pyrrole-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / 60 percent sodium hydride in oil / dimethylsulfoxide; diethyl ether / 0.08 h / 20 °C

2: 99 percent / potassium carbonate / dimethylformamide / 18 h / 90 °C

With sodium hydride; potassium carbonate; In diethyl ether; dimethyl sulfoxide; N,N-dimethyl-formamide; 1: Cycloaddition / 2: Methylation;