2,2-Diethyl-3-butenoic acid

Base Information

• Chemical Name: 2,2-Diethyl-3-butenoic acid
• CAS No.: 38477-05-3
• Molecular Formula: C₈H₁₄O₂
• Molecular Weight: 142.198
• Mol file: 38477-05-3.mol

Synonyms:2,2-Diethyl-3-butenoic acid

Chemical Property of 2,2-Diethyl-3-butenoic acid

Chemical Property:

• PSA: 37.30000
• LogP: 2.06340

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2-Diethyl-3-butenoic acid

There total 6 articles about 2,2-Diethyl-3-butenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

ethyl 2,2-diethylbut-3-enoate (42998-18-5) → 2,2-diethylbut-3-enoic acid (38477-05-3)

Guidance literature:

With sodium hydroxide; In ethanol; at 150 ℃; for 3h;

DOI:10.1002/jhet.5570420225

Reference yield:

1-bromo-3-ethylpent-2-ene (21378-06-3) + carbon dioxide (124-38-9,18923-20-1) → 2,2-diethylbut-3-enoic acid (38477-05-3) + 4-Ethyl-hex-3-enoic acid (55665-80-0)

Guidance literature:

With tetraethylammonium perchlorate; magnesium; In N,N-dimethyl-formamide; at -10 ℃; electrochemical reaction;

DOI:10.1016/0040-4039(95)00537-M

Reference yield:

1-chloro-3-ethylpent-2-ene (761-20-6) + carbon dioxide (124-38-9,18923-20-1) → 2,2-diethylbut-3-enoic acid (38477-05-3) + 4-Ethyl-hex-3-enoic acid (55665-80-0)

Guidance literature:

With tetraethylammonium perchlorate; magnesium; In N,N-dimethyl-formamide; at -10 ℃; electrochemical reaction;

DOI:10.1016/0040-4039(95)00537-M

upstream raw materials:

1-bromo-3-ethylpent-2-ene

carbon dioxide

1-chloro-3-ethylpent-2-ene

ethyl 2,2-diethylbut-3-enoate

Downstream raw materials:

N-(2-bromophenyl)-2,2-diethylbut-3-enamide

N-(2-bromo-4-methylphenyl)-2,2-diethylbut-3-enamide

N-(2-bromo-4-fluorophenyl)-2,2-diethylbut-3-enamide

N-(2-bromo-4-methoxyphenyl)-2,2-diethylbut-3-enamide

Refernces

• 1、 Tokuda, Masao,Kabuki, Takashi,Katoh, Yoshitaka,Suginome, Hiroshi. "Regioselective Synthesis of β,γ-Unsaturated Acids by the Electrochemical Carboxylation of Allylic Bromides Using a Reactive-metal Anode". . p. 3345 - 3348. Retrieved 2007/10/02.