6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride

Base Information

• Chemical Name: 6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride
• CAS No.: 154179-39-2
• Molecular Formula: C15H12Cl2N2O
• Molecular Weight: 307.179
• Hs Code.: 2933499090
• Mol file: 154179-39-2.mol

Synonyms:6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride;3-[(7-Chloroquinolin-4-yl)amino]phenol hydrochloride;6-[cis-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride

Chemical Property of 6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride

Chemical Property:

• PSA: 45.15000
• LogP: 5.21240

Purity/Quality:

98%min ^*data from raw suppliers

3-[(7-Chloroquinolin-4-yl)amino]phenolHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride

There total 1 articles about 6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4,7-dichloroquinoline (86-98-6,1138471-54-1) + m-Hydroxyaniline (591-27-5) → 7-chloro-4-[(3-hydroxyphenyl)amino]quinolinium chloride (154179-39-2)

Guidance literature:

In ethanol; Reflux;

DOI:10.1021/jm8012618

upstream raw materials:

4,7-dichloroquinoline

m-Hydroxyaniline