4,7-Dichloroquinoline

Base Information Edit

Chemical Name:4,7-Dichloroquinoline
CAS No.:86-98-6
Molecular Formula:C9H5Cl2N
Molecular Weight:198.051
Hs Code.:29334910
European Community (EC) Number:201-714-7
NSC Number:593
UNII:Z61O2HEQ2J
DSSTox Substance ID:DTXSID0052590
Nikkaji Number:J3.898I
Wikipedia:4,7-Dichloroquinoline
Wikidata:Q27295050
ChEMBL ID:CHEMBL319828
Mol file:86-98-6.mol

Synonyms:5-20-07-00316 (Beilstein Handbook Reference);AI3-50374;BRN 0125359;NSC 593;TL 1473;Quinoline, 4,7-dichloro-;

Suppliers and Price of 4,7-Dichloroquinoline

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
4,7-Dichloroquinoline
50g
$ 177.00

TRC
4,7-Dichloroquinoline
25 g
$ 120.00

TRC
4,7-Dichloroquinoline
5 g
$ 65.00

TRC
4,7-Dichloroquinoline
1g
$ 55.00

TCI Chemical
4,7-Dichloroquinoline >98.0%(GC)
25g
$ 28.00

SynQuest Laboratories
4,7-Dichloroquinoline 97%
500 g
$ 125.00

SynQuest Laboratories
4,7-Dichloroquinoline 97%
10 g
$ 10.00

SynQuest Laboratories
4,7-Dichloroquinoline 97%
100 g
$ 40.00

SynQuest Laboratories
4,7-Dichloroquinoline 97%
25 g
$ 20.00

Sigma-Aldrich
4,7-Dichloroquinoline ≥99%
25g
$ 62.10

Total 163 raw suppliers

Chemical Property of 4,7-Dichloroquinoline Edit

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:0.00313mmHg at 25°C
Melting Point:81-83 °C(lit.)
Refractive Index:1.66
Boiling Point:292.9 °C at 760 mmHg
PKA:1.99±0.27(Predicted)
Flash Point:158.7 °C
PSA：12.89000
Density:1.407 g/cm³
LogP:3.54160
Storage Temp.:Store below +30°C.
Solubility.:chloroform: soluble50mg/mL, clear, colorless to greenish-yellow
Water Solubility.:insoluble
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:196.9799046
Heavy Atom Count:12
Complexity:163

Purity/Quality:

99% ^*data from raw suppliers

4,7-Dichloroquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Nitrogen Compounds -> Quinolines
Canonical SMILES:C1=CC2=C(C=CN=C2C=C1Cl)Cl
Uses 4,7-Dichloroquinoline is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti -microbial agents showing efficacy against common bacterial strains. Chloroquinoline impurity. 4,7-Dichloroquinoline is used as a drug chloroquine phosphate intermediate. It is also is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti-microbial agents showing efficacy against common bacterial strains. 4,7-Dichloroquinoline was used in the synthesis of piperaquine. It was used as starting reagent in the synthesis of {3-amino-5-[(7-chloro-4-quinolyl)amino]phenyl}methanol.

Technology Process of 4,7-Dichloroquinoline

There total 30 articles about 4,7-Dichloroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%