3-[(2,5-dimethylphenyl)sulfamoyl]-4-methyl-N-(2-phenylphenyl)benzamide

Base Information

Chemical Name:3-[(2,5-dimethylphenyl)sulfamoyl]-4-methyl-N-(2-phenylphenyl)benzamide
CAS No.:824981-55-7
Molecular Formula:C28H26N2O3S
Molecular Weight:470.592
Hs Code.:
DSSTox Substance ID:DTXSID60367060
Wikidata:Q82152644
ChEMBL ID:CHEMBL1427860
Mol file:824981-55-7.mol

Synonyms:824981-55-7;MLS000582311;SF-22 (NPY Y2 antagonist);3-[(2,5-dimethylphenyl)sulfamoyl]-4-methyl-N-(2-phenylphenyl)benzamide;SMR000200850;N-(2-Biphenylyl)-3-[(2,5-dimethylphenyl)sulfamoyl]-4-methylbenzamide;N-(biphenyl-2-yl)-3-(N-(2,5-diMethylphenyl)sulfaMoyl)-4-MethylbenzaMide;N-2-biphenylyl-3-{[(2,5-dimethylphenyl)amino]sulfonyl}-4-methylbenzamide;MLS002547616;CHEMBL1427860;SCHEMBL15919821;BDBM42524;cid_2223246;DTXSID60367060;REGID_for_CID_2223246;HMS2442J16;STL100705;AKOS000378146;NCGC00485111-01;SF-22, >=98% (HPLC);N-(biphenyl-2-yl)-3-[(2,5-dimethylphenyl)sulfamoyl]-4-methylbenzamide

Suppliers and Price of 3-[(2,5-dimethylphenyl)sulfamoyl]-4-methyl-N-(2-phenylphenyl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
SF-22 ≥98% (HPLC)
25mg
$ 273.00

Sigma-Aldrich
SF-22 ≥98% (HPLC)
5mg
$ 68.80

American Custom Chemicals Corporation
SF-22 95.00%
25MG
$ 645.00

American Custom Chemicals Corporation
SF-22 95.00%
5MG
$ 462.00

Total 2 raw suppliers

Chemical Property of 3-[(2,5-dimethylphenyl)sulfamoyl]-4-methyl-N-(2-phenylphenyl)benzamide

Chemical Property:

PSA：87.14000
LogP:7.86970
Storage Temp.:room temp
Solubility.:DMSO: soluble26mg/mL
XLogP3:6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:470.16641387
Heavy Atom Count:34
Complexity:773

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

SF-22 ≥98% (HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)C)NS(=O)(=O)C2=C(C=CC(=C2)C(=O)NC3=CC=CC=C3C4=CC=CC=C4)C

Technology Process of 3-[(2,5-dimethylphenyl)sulfamoyl]-4-methyl-N-(2-phenylphenyl)benzamide

There total 2 articles about 3-[(2,5-dimethylphenyl)sulfamoyl]-4-methyl-N-(2-phenylphenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 884990-77-6
C₁₆H₁₇NO₄S

: 90-41-5
2-phenylaniline

: 824981-55-7
SF-22

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; Reagent/catalyst; Solvent; Temperature;

Reference yield:

: 95-78-3
2,5-Dimethylaniline

: 99-94-5
p-Toluic acid

: 824981-55-7
SF-22

Guidance literature:: Multi-step reaction with 2 steps

1.1: chlorosulfonic acid / Reflux

1.2: 20 °C

2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 °C

With chlorosulfonic acid; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide;