N-(2-methylbenzyl)cyclohexanamine

Base Information

Chemical Name:N-(2-methylbenzyl)cyclohexanamine
CAS No.:90504-90-8
Molecular Formula:C14H21N
Molecular Weight:203.327
Hs Code.:
DSSTox Substance ID:DTXSID10361159
Wikidata:Q82143339
ChEMBL ID:CHEMBL1906781

Synonyms:N-(2-methylbenzyl)cyclohexanamine;90504-90-8;CHEMBRDG-BB 6606285;N-[(2-METHYLPHENYL)METHYL]CYCLOHEXANAMINE;N-cyclohexyl-N-(2-methylbenzyl)amine;Oprea1_481577;AN-329/15537121;SCHEMBL9346814;CHEMBL1906781;DTXSID10361159;STK124763;AKOS000222607;EN300-167329

Suppliers and Price of N-(2-methylbenzyl)cyclohexanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of N-(2-methylbenzyl)cyclohexanamine

Chemical Property:

Vapor Pressure:0.000584mmHg at 25°C
Boiling Point:310.9°C at 760 mmHg
Flash Point:144.3°C
Density:0.96g/cm³
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:203.167399674
Heavy Atom Count:15
Complexity:172

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1CNC2CCCCC2

Technology Process of N-(2-methylbenzyl)cyclohexanamine

There total 4 articles about N-(2-methylbenzyl)cyclohexanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: N-(2-methylbenzylidene)cyclohexylamine

: 90504-90-8
N-[(2-methylphenyl)methyl]cyclohexanamine

Guidance literature:: With sodium tetrahydroborate; In ethanol; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1002/anie.201606354

Reference yield: 90.0%

: 95-46-5
2-methylphenyl bromide

: N-[(trifluoro-λ4-boranyl)methyl]cyclohexanaminium

: 90504-90-8
N-[(2-methylphenyl)methyl]cyclohexanamine

Guidance literature:: With chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)]palladium (II); caesium carbonate; In tetrahydrofuran; water; at 60 ℃; for 24h; Inert atmosphere;
DOI:10.1002/chem.201200831

Reference yield:

: 108-91-8,157973-60-9
cyclohexylamine

: 90504-90-8
N-[(2-methylphenyl)methyl]cyclohexanamine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran; tert-butyl alcohol / 12 h / 60 °C

2: chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)]palladium (II); caesium carbonate / tetrahydrofuran; water / 24 h / 60 °C / Inert atmosphere

With chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)]palladium (II); caesium carbonate; In tetrahydrofuran; water; tert-butyl alcohol; 2: Suzuki-Miyaura cross-coupling reaction;
DOI:10.1002/chem.201200831