1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione

Base Information

Chemical Name:1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione
CAS No.:269410-01-7
Molecular Formula:C₁₂H₁₉BN₂O₄
Molecular Weight:266.105
Hs Code.:
DSSTox Substance ID:DTXSID601124689
Nikkaji Number:J3.273.547I

Synonyms:269410-01-7;1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione;1,3-DIMETHYLURACIL-5-BORONIC ACID PINACOL ESTER;1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,4(1H,3H)-pyrimidinedione;1,3-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4-dione;SCHEMBL5899696;SZPDXKPAWVDDPF-UHFFFAOYSA-N;DTXSID601124689;MFCD07781230;AT16995;SB60753;BS-27761;CS-0176221;A903133

Suppliers and Price of 1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,3-Dimethyluracil-5-boronicacidpinacolester
100mg
$ 150.00

Crysdot
1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione 95+%
1g
$ 470.00

Chemenu
1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione 98%
1g
$ 722.00

American Custom Chemicals Corporation
1,3-DIMETHYLURACIL-5-BORONIC ACID PINACOL ESTER 95.00%
5MG
$ 495.58

Total 8 raw suppliers

Chemical Property of 1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione

Chemical Property:

Boiling Point:291.7±50.0 °C(Predicted)
PKA:-1.80±0.40(Predicted)
PSA：62.46000
Density:1.18±0.1 g/cm3(Predicted)
LogP:-0.61680
Storage Temp.:Room temperature.
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:266.1437873
Heavy Atom Count:19
Complexity:456

Purity/Quality:

97% ^*data from raw suppliers

1,3-Dimethyluracil-5-boronicacidpinacolester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CN(C(=O)N(C2=O)C)C

Technology Process of 1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione

There total 3 articles about 1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 40738-83-8
5-iodo-1,3-dimethyluracil

: 269410-01-7
1,3-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione

Guidance literature:: With triethylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; at 80 ℃; for 18h;

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; 5-iodo-1,3-dimethyluracil; In 1,4-dioxane; at 80 ℃; for 8h;

Reference yield:

: 874-14-6,156398-76-4
1,3-dimethyluracil

: 73183-34-3
bis(pinacol)diborane

: 269410-01-7
1,3-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione

: 1,3-dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione

Guidance literature:: With [2,2]bipyridinyl; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; In 1,4-dioxane; at 80 ℃; for 4h; Overall yield = 60 %; Overall yield = 40 mg; Inert atmosphere; Schlenk technique;
DOI:10.1055/s-0036-1588735

Reference yield:

: 874-14-6,156398-76-4
1,3-dimethyluracil

: 73183-34-3
bis(pinacol)diborane

: 269410-01-7
1,3-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4(1H,3H)-dione

: C₁₈H₃₀B₂N₂O₆

Guidance literature:: With 2,6-di-tert-butyl-pyridine; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; In tetrahydrofuran; at 80 ℃; for 24h; Sealed tube; Inert atmosphere;
DOI:10.3987/COM-14-12958