AIDS-011078

Base Information

• Chemical Name: AIDS-011078
• CAS No.: 90389-87-0
• Molecular Formula: C₁₀H₁₄FN
• Molecular Weight: 167.226
• Hs Code.: 2921499090
• Mol file: 90389-87-0.mol

Synonyms:

Chemical Property of AIDS-011078

Chemical Property:

• Vapor Pressure: 0.249mmHg at 25°C
• Boiling Point: 205.5°Cat760mmHg
• Flash Point: 78.1°C
• PSA: 12.03000
• Density: 0.991g/cm³
• LogP: 2.71460

Purity/Quality:

98%min ^*data from raw suppliers

N-(3-Fluorobenzyl)propan-2-amine hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of AIDS-011078

There total 4 articles about AIDS-011078 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.5%

→ N-(3-fluorobenzyl)propan-2-amine (90389-87-0)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In methanol; at 20 ℃; Inert atmosphere;

Reference yield: 42.0%

isopropylamine (75-31-0) + 1-(Bromomethyl)-3-fluorobenzene (456-41-7) → N-(3-fluorobenzyl)propan-2-amine (90389-87-0)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 6h;

DOI:10.1021/acs.jmedchem.1c01784

Reference yield:

[1-(3-Fluoro-phenyl)-meth-(E)-ylidene]-isopropyl-amine (46118-67-6) → N-(3-fluorobenzyl)propan-2-amine (90389-87-0)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2h; Heating;

DOI:10.1021/jm00375a005

upstream raw materials:

[1-(3-Fluoro-phenyl)-meth-(E)-ylidene]-isopropyl-amine

3-Fluorobenzaldehyde

isopropylamine

1-(Bromomethyl)-3-fluorobenzene