4-[(5Z)-5-BENZYLIDENE-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-3-YL]BENZOIC ACID

Base Information

Chemical Name:4-[(5Z)-5-BENZYLIDENE-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-3-YL]BENZOIC ACID
CAS No.:101439-76-3
Molecular Formula:C17H11NO3S2
Molecular Weight:341.4
Hs Code.:
Mol file:101439-76-3.mol

Synonyms:IFLAB-BB F0207-0150;4-[(5Z)-5-BENZYLIDENE-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-3-YL]BENZOIC ACID;BML-260;4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-thiazolidin-3-yl}-benzoic acid

Suppliers and Price of 4-[(5Z)-5-BENZYLIDENE-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-3-YL]BENZOIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(5-Benzylidene-4-oxo-2-thioxothiazolidin-3-yl)benzoicAcid
50mg
$ 200.00

Matrix Scientific
4-(5-Benzylidene-4-oxo-2-thioxothiazolidin-3-yl)benzoic acid 95%+
5g
$ 2848.00

Matrix Scientific
4-(5-Benzylidene-4-oxo-2-thioxothiazolidin-3-yl)benzoic acid 95%+
2.500g
$ 1889.00

Matrix Scientific
4-(5-Benzylidene-4-oxo-2-thioxothiazolidin-3-yl)benzoic acid 95%+
1g
$ 864.00

American Custom Chemicals Corporation
BML-260 95.00%
10MG
$ 199.50

Total 4 raw suppliers

Chemical Property of 4-[(5Z)-5-BENZYLIDENE-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-3-YL]BENZOIC ACID

Chemical Property:

PSA：115.00000
LogP:3.85560

Purity/Quality:

98%min ^*data from raw suppliers

4-(5-Benzylidene-4-oxo-2-thioxothiazolidin-3-yl)benzoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-[(5Z)-5-BENZYLIDENE-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-3-YL]BENZOIC ACID

There total 3 articles about 4-[(5Z)-5-BENZYLIDENE-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-3-YL]BENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 6322-60-7
4-(4-oxo-2-thioxo-thiazolidin-3-yl)-benzoic acid

: 100-52-7
benzaldehyde

: 101439-76-3
(Z)-4-(5-benzylidene-4-oxo-2-thioxothiazolidin-3-yl)benzoic acid

Guidance literature:: With ammonium acetate; acetic acid; at 120 ℃; for 4h;
DOI:10.1021/acsmedchemlett.7b00548

Reference yield:

: 150-13-0,159246-81-8,8014-65-1
4-amino-benzoic acid

: 101439-76-3
(Z)-4-(5-benzylidene-4-oxo-2-thioxothiazolidin-3-yl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / water / 16 h / 20 °C

1.2: 3 h / 20 °C

1.3: 16 h / Reflux

2.1: acetic acid; ammonium acetate / 4 h / 120 °C

With ammonium acetate; acetic acid; sodium hydroxide; In water; 2.1: |Knoevenagel Condensation;
DOI:10.1021/acsmedchemlett.7b00548