Thieno[3,2-b]thiophen-2-ylmethanol

Base Information

Chemical Name:Thieno[3,2-b]thiophen-2-ylmethanol
CAS No.:127025-34-7
Molecular Formula:C₇H₆OS₂
Molecular Weight:170.256
Hs Code.:
European Community (EC) Number:851-329-9
Mol file:127025-34-7.mol

Synonyms:127025-34-7;Thieno[3,2-b]thiophen-2-ylmethanol;Thieno[3,2-b]thiophen-2-yl-methanol;{Thieno[3,2-b]thiophen-2-yl}methanol;thieno[3,2-b]thiophen-5-ylmethanol;SCHEMBL5039924;TXYAZXBBBKENKC-UHFFFAOYSA-N;CFA02534;MFCD08059495;AKOS006284961;2-hydroxymethylthieno[3,2-b]-thiophene;AS-43752;CS-0215723;EN300-2922791;Z1198175580

Suppliers and Price of Thieno[3,2-b]thiophen-2-ylmethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Thieno[3,2-b]thiophen-2-ylmethanol

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:169.98600716
Heavy Atom Count:10
Complexity:129

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CSC2=C1SC(=C2)CO

Technology Process of Thieno[3,2-b]thiophen-2-ylmethanol

There total 1 articles about Thieno[3,2-b]thiophen-2-ylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 930-96-1
3-bromo-2-thiophenecarboxaldehyde

: 127025-34-7
2-(hydroxymethyl)thieno<3,2-b>thiophene

Guidance literature:: Multi-step reaction with 5 steps

1: 17.6 g / pyridinium tosylate / toluene / 1 h / Heating

3: p-toluenesulfonic acid hydrate / acetone / 1 h

4: 36.93 g / piperidine, acetic acid / benzene / 5 h / Heating

5: LiAlH₄ / diethyl ether / 3 h / Ambient temperature

With piperidine; lithium aluminium tetrahydride; pyridinium p-toluenesulfonate; toluene-4-sulfonic acid; acetic acid; In diethyl ether; acetone; toluene; benzene;
DOI:10.1021/jm00110a008

Reference yield: 97.0%

: 6399-81-1
triphenylphosphine hydrobromide

: 127025-34-7
2-(hydroxymethyl)thieno<3,2-b>thiophene

: C₂₅H₂₀PS₂⁽¹⁺⁾*Br^(1-)

Guidance literature:: In chloroform; for 3h; Reflux;
DOI:10.1039/c4tc01896f

Reference yield:

: 127025-34-7
2-(hydroxymethyl)thieno<3,2-b>thiophene

: C₄₀H₅₁NO₂S₂

Guidance literature:: Multi-step reaction with 4 steps

1.1: chloroform / 3 h / Reflux

2.1: sodium hydride / tetrahydrofuran / 24 h / 20 °C

3.1: n-butyllithium / tetrahydrofuran; hexane / 1.5 h / -78 - -10 °C / Inert atmosphere

3.2: -78 °C / Inert atmosphere

4.1: sodium ethanolate / ethanol / 0.5 h / 95 °C / Microwave irradiation

With n-butyllithium; sodium ethanolate; sodium hydride; In tetrahydrofuran; ethanol; hexane; chloroform; 2.1: |Wittig Olefination;
DOI:10.1039/c4tc01896f