5-(2-Hydroxy-2-propyl)-2-methylphenylboronic Acid Pinacol Ester

Base Information

Chemical Name:5-(2-Hydroxy-2-propyl)-2-methylphenylboronic Acid Pinacol Ester
CAS No.:1345961-02-5
Molecular Formula:C₁₆H₂₅BO₃
Molecular Weight:276.184
Hs Code.:
Mol file:1345961-02-5.mol

Synonyms:5-(2-Hydroxy-2-propyl)-2-methylphenylboronic Acid Pinacol Ester;2-(4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol

Suppliers and Price of 5-(2-Hydroxy-2-propyl)-2-methylphenylboronic Acid Pinacol Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 5-(2-Hydroxy-2-propyl)-2-methylphenylboronic Acid Pinacol Ester

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(2-Hydroxy-2-propyl)-2-methylphenylboronic Acid Pinacol Ester

There total 2 articles about 5-(2-Hydroxy-2-propyl)-2-methylphenylboronic Acid Pinacol Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 40180-81-2
2-(3-bromo-4-methylphenyl)propan-2-ol

: 73183-34-3
bis(pinacol)diborane

: 1345961-02-5
2-(3-bromo-4-methylphenyl)propan-2-ol

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In 1,4-dioxane; at 90 ℃; for 16h; Inert atmosphere;
DOI:10.1016/j.bmcl.2016.01.021

Reference yield:

: 104901-43-1
methyl 3-bromo-4-methylbenzoate

: 1345961-02-5
2-(3-bromo-4-methylphenyl)propan-2-ol

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

2: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 90 °C / Inert atmosphere

With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran; 1,4-dioxane;

Reference yield: 80.0%

: 1345961-02-5
2-(3-bromo-4-methylphenyl)propan-2-ol

: 1276676-86-8
5-chloro-1-(2,2-dimethylpropyl)-3-methyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one

: 1352421-24-9
1-(2,2-dimethylpropyl)-5-[5-(2-hydroxypropan-2-yl)-2-methylphenyl]-3-methyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one

Guidance literature:: With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; In tetrahydrofuran; water; at 66 ℃; Inert atmosphere;
DOI:10.1016/j.bmcl.2016.01.021