4,4,5,5-Tetramethyl-2-[2-[(trimethylsilyl)ethynyl]phenyl]-1,3,2-dioxaborolane

Base Information

• Chemical Name: 4,4,5,5-Tetramethyl-2-[2-[(trimethylsilyl)ethynyl]phenyl]-1,3,2-dioxaborolane
• CAS No.: 1218790-52-3
• Molecular Formula: C₁₇H₂₅BO₂Si
• Molecular Weight: 300.281
• Hs Code.: 2934999090
• Mol file: 1218790-52-3.mol

Synonyms:2-[(Trimethylsilyl)ethynyl]phenylboronic acid pinacol ester;4,4,5,5-Tetramethyl-2-[2-[(trimethylsilyl)ethynyl]phenyl]-1,3,2-dioxaborolane;trimethyl(2-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethynyl)silane;Trimethyl((2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethynyl)silane

Chemical Property of 4,4,5,5-Tetramethyl-2-[2-[(trimethylsilyl)ethynyl]phenyl]-1,3,2-dioxaborolane

Chemical Property:

• Refractive Index: n20/D 1.514
• Flash Point: 110 °C
• PSA: 18.46000
• Density: 0.959 g/mL at 25 °C
• LogP: 3.21470
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

2-[(Trimethylsilyl)ethynyl]phenylboronic acid pinacol ester 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4,5,5-Tetramethyl-2-[2-[(trimethylsilyl)ethynyl]phenyl]-1,3,2-dioxaborolane

There total 1 articles about 4,4,5,5-Tetramethyl-2-[2-[(trimethylsilyl)ethynyl]phenyl]-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-1-(trimethylsilylethynyl)benzene (38274-16-7) + bis(pinacol)diborane (73183-34-3) → trimethyl((2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethynyl)silane (1218790-52-3)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 85 ℃; Inert atmosphere;

Reference yield:

trimethyl((2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethynyl)silane (1218790-52-3) → 9,9-bis(4-methoxyphenyl)-9H-benzo[4',5']thieno[2',3':4,5]thieno[3,2-h]naphtho[2,1-f]chromene

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium carbonate; bis-triphenylphosphine-palladium(II) chloride / ethanol; toluene; water / 2 h / 70 °C / Inert atmosphere

2.1: potassium carbonate / methanol; dichloromethane / 4 h / 20 °C

2.2: 8 h / 80 °C / Inert atmosphere

3.1: dodecylbenzenesulfonic acid / 1,2-dichloro-ethane / 1 h / 100 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; potassium carbonate; In methanol; ethanol; dichloromethane; water; 1,2-dichloro-ethane; toluene;

upstream raw materials:

2-bromo-1-(trimethylsilylethynyl)benzene

bis(pinacol)diborane

Refernces