(S)-Alogliptin Benzoate Salt

Base Information

Chemical Name:(S)-Alogliptin Benzoate Salt
CAS No.:1638544-64-5
Molecular Formula:C25H27N5O4
Molecular Weight:461.51298
Hs Code.:
Mol file:1638544-64-5.mol

Synonyms:(S)-Alogliptin Benzoate Salt

Suppliers and Price of (S)-Alogliptin Benzoate Salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-AlogliptinBenzoateSalt
100mg
$ 450.00

TRC
(S)-AlogliptinBenzoateSalt
10mg
$ 50.00

Total 5 raw suppliers

Chemical Property of (S)-Alogliptin Benzoate Salt

Chemical Property:

PSA：134.35000
LogP:2.54458
Storage Temp.:Refrigerator, Under inert atmosphere
Solubility.:Chloroform (Slightly, Sonicated), Ethanol (Slightly, Heated, Sonicated), Methano

Purity/Quality:

97% ^*data from raw suppliers

(S)-AlogliptinBenzoateSalt ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (S)-Alogliptin Benzoate Salt is an impurity of Alogliptin (A575425), which is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4).Antidiabetic agent.

Technology Process of (S)-Alogliptin Benzoate Salt

There total 27 articles about (S)-Alogliptin Benzoate Salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.7%

: 850649-61-5,1108732-05-3
alogliptin

: 65-85-0,8013-63-6
benzoic acid

: 1638544-64-5,850649-62-6
Alogliptin benzoate

Guidance literature:: In ethanol; at 50 - 80 ℃;

Reference yield: 91.7%

: 1246610-75-2
Alogliptin hydrochloride

: 65-85-0,8013-63-6
benzoic acid

: 1638544-64-5,850649-62-6
Alogliptin benzoate

Guidance literature:: Alogliptin hydrochloride; With sodium carbonate; In chloroform; at 25 ℃; for 0.333333h; Large scale;

benzoic acid; In ethanol; at 0 - 50 ℃; for 5h; Solvent; Large scale;

Reference yield: 88.9%

: benzyl N-[(3R)-1-{3-[(2-cyanophenyl)methyl]-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl}piperidin-3-yl]carbamate

: 65-85-0,8013-63-6
benzoic acid

: 1638544-64-5,850649-62-6
Alogliptin benzoate

Guidance literature:: benzyl N-[(3R)-1-{3-[(2-cyanophenyl)methyl]-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl}piperidin-3-yl]carbamate; With 5%-palladium/activated carbon; In 2-methyltetrahydrofuran; at 20 ℃; for 5h;

benzoic acid; In isopropyl alcohol; at 60 ℃; for 1h; Solvent;