(S)-2-Bromo-1-(2,4-dichlorophenyl)ethanol

Base Information

Chemical Name:(S)-2-Bromo-1-(2,4-dichlorophenyl)ethanol
CAS No.:187164-20-1
Molecular Formula:C₈H₇BrCl₂O
Molecular Weight:269.953
Hs Code.:
DSSTox Substance ID:DTXSID701238796

Synonyms:(S)-2-Bromo-1-(2,4-dichlorophenyl)ethanol;187164-20-1;(1s)-2-bromo-1-(2,4-dichlorophenyl)ethanol;(1S)-2-BROMO-1-(2,4-DICHLOROPHENYL)-1-ETHANOL;SCHEMBL7455141;DTXSID701238796;AKOS020850537;(alphaS)-alpha-(Bromomethyl)-2,4-dichlorobenzenemethanol

Suppliers and Price of (S)-2-Bromo-1-(2,4-dichlorophenyl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (S)-2-Bromo-1-(2,4-dichlorophenyl)ethanol

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:267.90573
Heavy Atom Count:12
Complexity:145

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Cl)Cl)C(CBr)O
Isomeric SMILES:C1=CC(=C(C=C1Cl)Cl)[C@@H](CBr)O

Technology Process of (S)-2-Bromo-1-(2,4-dichlorophenyl)ethanol

There total 3 articles about (S)-2-Bromo-1-(2,4-dichlorophenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 2631-72-3
2,4-dichlorophenacyl bromide

: 187164-20-1
(S)-2-bromo-1-(2,4-dichlorophenyl)ethan-1-ol

Guidance literature:: With B-chlorodiisopinocampheylborane; In tetrahydrofuran; at -25 ℃; for 16h;
DOI:10.1016/j.bmcl.2005.03.115

Reference yield:

borane-THF: borane-THF

: 2631-72-3
2,4-dichlorophenacyl bromide

: 112022-81-8,133261-83-3
(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

: 187164-20-1
(S)-2-bromo-1-(2,4-dichlorophenyl)ethan-1-ol

Guidance literature:: In tetrahydrofuran; methanol;

Reference yield:

: 2631-72-3
2,4-dichlorophenacyl bromide

: 187164-20-1
(S)-2-bromo-1-(2,4-dichlorophenyl)ethan-1-ol

: 860439-01-6
(R)-2-bromo-1-(2,4-dichlorophenyl)ethanol

Guidance literature:: With alcohol dehydrogenase PR₂; isopropyl alcohol; NADPH; at 30 ℃; for 24h; pH=7.5; optical yield given as %ee; TRIS-HBr-HCl buffer; Enzymatic reaction;
DOI:10.1021/jo102459w