Cob(I)alamin

Base Information

• Chemical Name: Cob(I)alamin
• CAS No.: 18534-66-2
• Molecular Formula: C62H89 Co N13 O14 P
• Molecular Weight: 1329.43
• Mol file: 18534-66-2.mol

Synonyms:Cobinamide,hydride hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with5,6-dimethyl-1-a-D-ribofuranosylbenzimidazole(8CI); Cob(I)alamin; Cob(I)alamin; Cobalamin, hydrido-; Hydridocobalamin;Vitamin B12s

Chemical Property of Cob(I)alamin

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 432.65000
• Density: g/cm³
• LogP: 5.32010
• Storage Temp.: -20°C

Purity/Quality:

99%, ^*data from raw suppliers

CBL ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cob(I)alamin

There total 2 articles about Cob(I)alamin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

vitamin B12 → vitamin B12s (18534-66-2)

Guidance literature:

With lithium perchlorate; In N,N-dimethyl-formamide; Electrolysis; the soln. of vitamin B12s was prepared by bulk electrolysis at -1 V at visible light or at -1.6 V in the dark; not isolated; determined from the anodic current of cyclic voltammogramms on the Co(I)/Co(II) wave;

Reference yield:

methylcobalamin (13422-55-4) → [Co(I)cobalamin] (18534-66-2)

Guidance literature:

In water; byproducts: CH4; Electrolysis; electrolysis at -1.5 V at pH 8.7; not isolated, detected by UV and cyclic voltammetry;

DOI:10.1021/ic00139a062

Reference yield:

vitamin B12s (18534-66-2) → hydroxocobalamin (795216-66-9,13422-51-0,53701-56-7)

Guidance literature:

With IrCl₆^(2-) or Fe(III)aq. or Fe(III)EDTA; In water; Kinetics;

upstream raw materials:

methylcobalamin

Downstream raw materials:

europium(II)

titanium(III)

hydroxocobalamin

uranium⁽⁴⁺⁾

Refernces

• 1、 Walder, Lorenz,Orlinski, Richard. "Mechanism of the light-assisted nucleophilic acylation of activated olefins catalyzed by vitamin B12". . p. 1606 - 1613. Retrieved 2008/10/08.