1-Azetidinecarboxaldehyde, 2,4-bis(hydroxymethyl)-, (2S,4S)- (9CI)

Base Information

Chemical Name:1-Azetidinecarboxaldehyde, 2,4-bis(hydroxymethyl)-, (2S,4S)- (9CI)
CAS No.:351075-56-4
Molecular Formula:C₆H₁₁NO₃
Molecular Weight:145.158
Hs Code.:
Mol file:351075-56-4.mol

Synonyms:1-Azetidinecarboxaldehyde, 2,4-bis(hydroxymethyl)-, (2S,4S)- (9CI)

Suppliers and Price of 1-Azetidinecarboxaldehyde, 2,4-bis(hydroxymethyl)-, (2S,4S)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Azetidinecarboxaldehyde, 2,4-bis(hydroxymethyl)-, (2S,4S)- (9CI)

Chemical Property:

PSA：60.77000
LogP:-0.85590

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-Azetidinecarboxaldehyde, 2,4-bis(hydroxymethyl)-, (2S,4S)- (9CI)

There total 2 articles about 1-Azetidinecarboxaldehyde, 2,4-bis(hydroxymethyl)-, (2S,4S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 351075-69-9
(2S,4S)-1-benzylazetidine-2,4-dimethanol

: 351075-56-4,168648-14-4
(2S,4S)-2,4-bis(hydroxymethyl)azetidine-1-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd(OH)2/C / methanol / 29 h / 20 °C / 3800 Torr

2: methanol / 64.75 h / 20 - 80 °C

With hydrogen; palladium dihydroxide; In methanol;
DOI:10.1016/S0957-4166(01)00077-5

Reference yield:

: 107-31-3
Methyl formate

: 351075-55-3
(2S,4S)-azetidine-2,4-dimethanol

: 351075-56-4,168648-14-4
(2S,4S)-2,4-bis(hydroxymethyl)azetidine-1-carbaldehyde

Guidance literature:: In methanol; at 20 - 80 ℃; for 64.75h;
DOI:10.1016/S0957-4166(01)00077-5

Reference yield:

: 351075-56-4,168648-14-4
(2S,4S)-2,4-bis(hydroxymethyl)azetidine-1-carbaldehyde

: (2S,4S)-2,4-bis(benzyloxymethyl)azetidine

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / tetrahydrofuran

2: 444 mg / aq. NaOH / methanol / 38 h / Heating

With sodium hydroxide; sodium hydride; In tetrahydrofuran; methanol;
DOI:10.1016/S0957-4166(01)00077-5