PSI 7411

Base Information

• Chemical Name: PSI 7411
• CAS No.: 1015073-43-4
• Molecular Formula: C₁₀H₁₄FN₂O₈P
• Molecular Weight: 0
• Mol file: 1015073-43-4.mol

Synonyms:PSI 7411

Chemical Property of PSI 7411

Chemical Property:

Purity/Quality:

NLT 98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PSI 7411

There total 1 articles about PSI 7411 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2'-deoxy-2'-fluoro-2'-methyluridine (863329-66-2,2041584-99-8) → GS-606965 (1015073-43-4)

Guidance literature:

With 1-methyl-1H-imidazole; trimethyl phosphite; trichlorophosphate; at 20 ℃;

DOI:10.1021/acs.jmedchem.9b00143

Reference yield:

GS-606965 (1015073-43-4) + benzyl bromide (100-39-0) → C17H20FN2O8P

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In acetonitrile; for 16h; Reflux;

Reference yield:

GS-606965 (1015073-43-4) → GS-461203 (1015073-42-3)

Guidance literature:

With bis(tetra-n-butylammonium) dihydrogen pyrophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 1.5h;

DOI:10.1021/acs.jmedchem.9b00143

upstream raw materials:

2'-deoxy-2'-fluoro-2'-methyluridine

Downstream raw materials:

GS-461203

Refernces