octadecan-3-ol

Base Information

• Chemical Name: octadecan-3-ol
• CAS No.: 111897-18-8
• Molecular Formula: C18H38O
• Molecular Weight: 270.49
• Mol file: 111897-18-8.mol

Synonyms:3-octadecanol

Chemical Property of octadecan-3-ol

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 51°C
• Refractive Index: 1.4290
• Boiling Point: 331.643°C at 760 mmHg
• Flash Point: 124.91°C
• PSA: 20.23000
• Density: 0.836g/cm³
• LogP: 6.23860

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of octadecan-3-ol

There total 7 articles about octadecan-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

octadecan-3-one (18261-92-2) → n-Octadecanol-(3) (111897-18-8,116724-03-9)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

Reference yield:

acetic acid-(1-ethyl-hexadecyl ester) (95554-34-0) → (R)-3-octadecanol (111897-18-8,116724-03-9)

Guidance literature:

With Burkholderica cepacia amano lipase; In acetone; at 25 ℃; pH=7.2; optical yield given as %ee; enantioselective reaction; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1016/j.tetasy.2011.07.017

Reference yield:

octadecan-3-one (18261-92-2) → (R)-3-octadecanol (111897-18-8,116724-03-9)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium tetrahydroborate / tetrahydrofuran; methanol / 0 - 5 °C

2: Amberlist 15 / 0.5 h / 25 °C

3: Burkholderica cepacia amano lipase / acetone / 25 °C / pH 7.2 / aq. phosphate buffer; Enzymatic reaction

With sodium tetrahydroborate; Burkholderica cepacia amano lipase; In tetrahydrofuran; methanol; acetone;

DOI:10.1016/j.tetasy.2011.07.017

upstream raw materials:

octadecan-3-one

1-hexadecylcarboxylic acid

acetic acid-(1-ethyl-hexadecyl ester)

n-Octadecanol-(3)

Downstream raw materials:

(R)-3-octadecanol

Refernces