4,7-Bis(5-broMothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5] thiadiazole

Base Information

Chemical Name:4,7-Bis(5-broMothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5] thiadiazole
CAS No.:1304773-89-4
Molecular Formula:C14H4Br2F2N2S3
Molecular Weight:494.202
Hs Code.:
Mol file:1304773-89-4.mol

Synonyms:4,7-Bis(5-broMothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5] thiadiazole;4,7-Bis(2-bromo-5-thienyl)-5,6-difluoro-2,1,3-benzothiadiazole

Suppliers and Price of 4,7-Bis(5-broMothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5] thiadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4,7-Bis(5-bromothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5]thiadiazole 97%
1g
$ 333.00

Arctom
4,7-Bis(5-bromothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5]thiadiazole 98%
250mg
$ 114.00

Arctom
4,7-Bis(5-bromothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5]thiadiazole 98%
1g
$ 346.00

Alichem
4,7-Bis(5-bromothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5]thiadiazole
1g
$ 400.00

Total 26 raw suppliers

Chemical Property of 4,7-Bis(5-broMothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5] thiadiazole

Chemical Property:

Boiling Point:510.7±45.0 °C(Predicted)
PKA:-3.42±0.50(Predicted)
PSA：110.50000
Density:1.978±0.06 g/cm3(Predicted)
LogP:6.95150

Purity/Quality:

99%, ^*data from raw suppliers

4,7-Bis(5-bromothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5]thiadiazole 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4,7-Bis(5-broMothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5] thiadiazole

There total 13 articles about 4,7-Bis(5-broMothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5] thiadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1304773-88-3
5,6-difluoro-4,7-di(thiophen-2-yl)benzo[c][1, 2, 5]thiadiazole

: 1304773-89-4
4,7-bis(5-bromothiophen-2-yl)-5,6-difluorobenzo[c]-[1,2,5]thiadiazole

Guidance literature:: With N-Bromosuccinimide; In 1,2-dichloro-benzene; at 55 ℃; for 3h;

Reference yield:

: 76179-40-3
2-amino-4,5-difluoroaniline

: 1304773-89-4
4,7-bis(5-bromothiophen-2-yl)-5,6-difluorobenzo[c]-[1,2,5]thiadiazole

Guidance literature:: Multi-step reaction with 5 steps

1.1: triethylamine; thionyl chloride / chloroform / 72 h / Inert atmosphere; Reflux

2.1: diisopropylamine; n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere

2.2: 3 h / -78 °C / Inert atmosphere

3.1: bromine / chloroform / 48 h / 60 °C / Darkness

4.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene; N,N-dimethyl-formamide / 12 h / 110 °C / Inert atmosphere

4.2: 2 h / 20 °C / Inert atmosphere

5.1: acetic acid; N-Bromosuccinimide / chloroform / 1 h / 0 °C

With N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; thionyl chloride; bromine; acetic acid; triethylamine; diisopropylamine; In tetrahydrofuran; hexane; chloroform; N,N-dimethyl-formamide; toluene;
DOI:10.1039/c3ta13686h

Reference yield:

: 1293389-28-2
5,6‐difluoro‐2,1,3‐benzothiadiazole

: 1304773-89-4
4,7-bis(5-bromothiophen-2-yl)-5,6-difluorobenzo[c]-[1,2,5]thiadiazole

Guidance literature:: Multi-step reaction with 3 steps

1: silver sulfate; iodine; sulfuric acid / 120.5 h / 20 - 110 °C / Inert atmosphere

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 48 h / Inert atmosphere; Reflux

3: N-Bromosuccinimide / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

With N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sulfuric acid; iodine; silver sulfate; In tetrahydrofuran; toluene;
DOI:10.1002/chem.201201321 DOI:10.1002/chem.201201321