6-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)quinazoline

Base Information

Chemical Name:6-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)quinazoline
CAS No.:1375301-92-0
Molecular Formula:C14H17BN2O2
Molecular Weight:256.10798
Hs Code.:2934999090
Mol file:1375301-92-0.mol

Synonyms:6-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)quinazoline;Quinazoline, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

Suppliers and Price of 6-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)quinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline
5mg
$ 60.00

Crysdot
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline 95%
100mg
$ 191.00

Crysdot
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline 95%
1g
$ 762.00

Ambeed
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline 95%
1g
$ 563.00

Ambeed
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline 95%
250mg
$ 226.00

Ambeed
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline 95%
100mg
$ 108.00

Total 8 raw suppliers

Chemical Property of 6-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)quinazoline

Chemical Property:

Boiling Point:390.5±15.0 °C(Predicted)
PKA:3?+-.0.26(Predicted)
PSA：44.24000
Density:1.14±0.1 g/cm3(Predicted)
LogP:1.92900
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)quinazoline

There total 1 articles about 6-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.9%

: 89892-21-7
6-bromoquinazoline

: 73183-34-3
bis(pinacol)diborane

: 1375301-92-0
6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,2-dimethoxyethane; at 80 ℃; for 4h; Inert atmosphere;

Reference yield:

: 1375301-92-0
6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline

: tert-butyl ((S)-1-((2S,4R)-2-((4-bromobenzyl)carbamoyl)-4-hydroxypyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate

: N¹-(2-(4-((Z)-1,2-Diphenylbut-1-en-1-yl)phenoxy)ethyl)-N¹¹-((S)-1-((2S,4R)-4-hydroxy-2-((4-(quinazolin-6-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-N¹-methylundecanediamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium acetate / 1,4-dioxane; water / 3 h / 90 °C

2.1: hydrogenchloride / 1,4-dioxane; methanol / 20 °C

2.2: 20 °C

With hydrogenchloride; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium acetate; In 1,4-dioxane; methanol; water; 1.1: |Suzuki Coupling;