1H-Pyrrole-1-carboxylic acid, 4-acetyl-2,3-dihydro-, methyl ester (9CI)

Base Information

Chemical Name:1H-Pyrrole-1-carboxylic acid, 4-acetyl-2,3-dihydro-, methyl ester (9CI)
CAS No.:82483-64-5
Molecular Formula:C₈H₁₁NO₃
Molecular Weight:169.18
Hs Code.:
Mol file:82483-64-5.mol

Synonyms:1H-Pyrrole-1-carboxylic acid, 4-acetyl-2,3-dihydro-, methyl ester (9CI)

Suppliers and Price of 1H-Pyrrole-1-carboxylic acid, 4-acetyl-2,3-dihydro-, methyl ester (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 4 raw suppliers

Chemical Property of 1H-Pyrrole-1-carboxylic acid, 4-acetyl-2,3-dihydro-, methyl ester (9CI)

Chemical Property:

Melting Point:107.5 - 109 °C (ethyl acetate)
PSA：46.61000
LogP:0.86930

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of 1H-Pyrrole-1-carboxylic acid, 4-acetyl-2,3-dihydro-, methyl ester (9CI)

There total 3 articles about 1H-Pyrrole-1-carboxylic acid, 4-acetyl-2,3-dihydro-, methyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: 76460-88-3
N-methoxycarbonyl-2,3-dihydropyrrole

: 75-36-5
acetyl chloride

: 82483-64-5
N-carbomethoxy-3-acetyl-2-pyrroline

Guidance literature:: With tin(IV) chloride; In dichloromethane; at -70 ℃; for 3h;
DOI:10.1016/S0040-4039(00)87059-8 DOI:10.1021/ja00388a037

Reference yield:

: 56475-88-8
methyl 2-methoxypyrrolidine-1-carboxylate

: 82483-64-5
N-carbomethoxy-3-acetyl-2-pyrroline

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / NH₄Cl / 3 h / 20 - 100 Torr / Heating

2: 32 percent / SnCl₄ / CH₂Cl₂ / 3 h / -70 °C

With tin(IV) chloride; ammonium chloride; In dichloromethane;
DOI:10.1021/ja00388a037

Reference yield:

: 56475-80-0
N-(methoxycarbonyl)pyrrolidine

: 82483-64-5
N-carbomethoxy-3-acetyl-2-pyrroline

Guidance literature:: Multi-step reaction with 3 steps

1: anodic oxidation in tetraethylammonium p-toluenesulfonate

2: 91 percent / NH₄Cl / 3 h / 20 - 100 Torr / Heating

3: 32 percent / SnCl₄ / CH₂Cl₂ / 3 h / -70 °C

With tin(IV) chloride; ammonium chloride; In dichloromethane;
DOI:10.1021/ja00388a037