2-Amino-3-bromo-6-hydroxypyridine

Base Information

Chemical Name:2-Amino-3-bromo-6-hydroxypyridine
CAS No.:511541-62-1
Molecular Formula:C5H5BrN2O
Molecular Weight:189.01
Hs Code.:
DSSTox Substance ID:DTXSID50576508
Wikidata:Q82466241
Mol file:511541-62-1.mol

Synonyms:511541-62-1;2-Amino-3-bromo-6-hydroxypyridine;6-Amino-5-bromopyridin-2-ol;6-amino-5-bromo-1H-pyridin-2-one;6-amino-5-bromo-pyridin-2-ol;6-Amino-5-bromopyridin-2(1H)-one;SCHEMBL508538;DTXSID50576508;IRLSARFYDLKHPS-UHFFFAOYSA-N;AKOS027351637;CS-0380545;G67431

Suppliers and Price of 2-Amino-3-bromo-6-hydroxypyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
2-Amino-3-bromo-6-hydroxypyridine
5g
$ 3890.00

Total 7 raw suppliers

Chemical Property of 2-Amino-3-bromo-6-hydroxypyridine

Chemical Property:

Boiling Point:294.4±40.0 °C(Predicted)
PKA:8.27±0.10(Predicted)
PSA：59.14000
Density:1.826±0.06 g/cm3(Predicted)
LogP:1.71310
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:187.95853
Heavy Atom Count:9
Complexity:207

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-3-bromo-6-hydroxypyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=O)NC(=C1Br)N

Technology Process of 2-Amino-3-bromo-6-hydroxypyridine

There total 2 articles about 2-Amino-3-bromo-6-hydroxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 5154-00-7
6-aminopyridine-2(1H)-one

: 511541-62-1
6-amino-5-bromo-2(1H)-pyridone

Guidance literature:: With bromine; acetic acid; at 20 ℃; for 0.5h;
DOI:10.1016/S0040-4039(00)92144-0

Reference yield:

: 5154-00-7,59315-47-8
6-amino-pyridin-2-ol

: 511541-62-1
6-amino-5-bromopyridin-2-ol

Guidance literature:: With bromine; In acetic acid; for 0.333333h; Inert atmosphere;

Reference yield: 73.0%

: 960071-95-8
(2R,3S,5R)-2-(4,4′-dimethoxytrityloxymethyl)-5-ethynyl-3-hydroxytetrahydrofuran

: 511541-62-1
6-amino-5-bromo-2(1H)-pyridone

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 1304073-48-0
(2R,3S,5R)-5-(6-(dimethylaminomethyleneamino)-2(1H)-pyridinon-5-ylethynyl)-2-(4,4'-dimethoxytrityloxymethyl)-3-hydroxytetrahydrofuran

Guidance literature:: (2R,3S,5R)-2-(4,4′-dimethoxytrityloxymethyl)-5-ethynyl-3-hydroxytetrahydrofuran; 6-amino-5-bromo-2(1H)-pyridone; N,N-dimethyl-formamide; With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; copper(l) iodide; triphenylphosphine; at 120 ℃; for 1h; Inert atmosphere;

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.3987/COM-10-S(E)89