4-Amino-1-benzylpyrrolidin-2-one hydrochloride

Base Information

Chemical Name:4-Amino-1-benzylpyrrolidin-2-one hydrochloride
CAS No.:478832-05-2
Molecular Formula:C11H15ClN2O
Molecular Weight:226.706
Hs Code.:2933790090
European Community (EC) Number:827-810-4
DSSTox Substance ID:DTXSID40594938
Mol file:478832-05-2.mol

Synonyms:4-amino-1-benzylpyrrolidin-2-one hydrochloride;478832-05-2;4-AMINO-1-BENZYL-PYRROLIDIN-2-ONE HYDROCHLORIDE;4-amino-1-benzylpyrrolidin-2-one;hydrochloride;C11H15ClN2O;4-AMINO-1-BENZYLPYRROLIDIN-2-ONE HCL;4-Amino-1-benzylpyrrolidin-2-oneHydrochloride;MFCD09743237;4-amino-1-benzyl-2-pyrrolidinone hydrochloride;SCHEMBL5412784;AMY4292;DTXSID40594938;BWOHUVMBCGXODG-UHFFFAOYSA-N;AKOS008132138;DS-3975;SB37309;SY024471;DB-331985;CS-0072163;EN300-42163;A872036;F2147-0033;Z425632448;4-amino-1-benzylpyrrolidin-2-one hydrochloride, AldrichCPR;4-Amino-1-benzylpyrrolidin-2-one--hydrogen chloride (1/1)

Suppliers and Price of 4-Amino-1-benzylpyrrolidin-2-one hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Amino-1-benzylpyrrolidin-2-onehydrochloride
500mg
$ 100.00

Matrix Scientific
4-Amino-1-benzylpyrrolidin-2-onehydrochloride 95%+
2.500g
$ 762.00

Matrix Scientific
4-Amino-1-benzylpyrrolidin-2-onehydrochloride 95%+
500mg
$ 218.00

Matrix Scientific
4-Amino-1-benzylpyrrolidin-2-onehydrochloride 95%+
100mg
$ 83.00

J&W Pharmlab
4-Amino-1-benzyl-pyrrolidin-2-onehydrochloride 98%
500mg
$ 88.00

J&W Pharmlab
4-Amino-1-benzyl-pyrrolidin-2-onehydrochloride 98%
25g
$ 1192.00

Crysdot
4-Amino-1-benzylpyrrolidin-2-onehydrochloride 95+%
10g
$ 507.00

Crysdot
4-Amino-1-benzylpyrrolidin-2-onehydrochloride 95+%
25g
$ 924.00

Crysdot
4-Amino-1-benzylpyrrolidin-2-onehydrochloride 95+%
1g
$ 103.00

Crysdot
4-Amino-1-benzylpyrrolidin-2-onehydrochloride 95+%
5g
$ 308.00

Total 12 raw suppliers

Chemical Property of 4-Amino-1-benzylpyrrolidin-2-one hydrochloride

Chemical Property:

PSA：46.33000
LogP:2.18640
Storage Temp.:Inert atmosphere,Room Temperature
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:226.0872908
Heavy Atom Count:15
Complexity:211

Purity/Quality:

99%, ^*data from raw suppliers

4-Amino-1-benzylpyrrolidin-2-onehydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 43
Safety Statements: 36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CN(C1=O)CC2=CC=CC=C2)N.Cl

Technology Process of 4-Amino-1-benzylpyrrolidin-2-one hydrochloride

There total 3 articles about 4-Amino-1-benzylpyrrolidin-2-one hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 478832-03-0
tert-butyl 1-benzyl-5-oxo-3-pyrrolidinylcarbamate

: 478832-05-2
1-benzyl-4(S)-amino-2-pyrrolidinone hydrochloride

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; 1,4-dioxane; at 20 ℃;

Reference yield:

: 5733-86-8
1-benzyl-5-oxopyrrolidine-3-carboxylic acid

: 478832-05-2
1-benzyl-4(S)-amino-2-pyrrolidinone hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: diphenylphosphoranyl azide; triethylamine / 2 h / Heating / reflux

2: hydrogenchloride / tetrahydrofuran; 1,4-dioxane / 20 °C

With hydrogenchloride; diphenylphosphoranyl azide; triethylamine; In tetrahydrofuran; 1,4-dioxane;

Reference yield:

: 51535-00-3
methyl 1-benzyl-5-oxo-3-pyrrolidinecarboxylate

: 478832-05-2
1-benzyl-4(S)-amino-2-pyrrolidinone hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: lithium hydroxide / tetrahydrofuran; methanol; water / 0.33 h / Heating / reflux

2: diphenylphosphoranyl azide; triethylamine / 2 h / Heating / reflux

3: hydrogenchloride / tetrahydrofuran; 1,4-dioxane / 20 °C

With hydrogenchloride; lithium hydroxide; diphenylphosphoranyl azide; triethylamine; In tetrahydrofuran; 1,4-dioxane; methanol; water;