N',N'-Di(desmethyl) Azithromycin

Base Information

Chemical Name:N',N'-Di(desmethyl) Azithromycin
CAS No.:612069-27-9
Molecular Formula:C₃₆H₆₈N₂O₁₂
Molecular Weight:720.942
Hs Code.:
Mol file:612069-27-9.mol

Synonyms:N',N'-Di(desmethyl) Azithromycin;3'-N,N-Di(desMethyl) AzithroMycin;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(3-AMino-3,4,6-trideoxy-β-D-xylo-hexopyranosyl)oxy]-13-[(2,6-dideoxy-3-C-Methyl-3-O-Methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptaMethyl-1-oxa-

Suppliers and Price of N',N'-Di(desmethyl) Azithromycin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3’-N,N-Di(desmethyl)Azithromycin
5mg
$ 205.00

TRC
3’-N,N-Di(desmethyl)Azithromycin
50mg
$ 1620.00

American Custom Chemicals Corporation
AZITHROMYCIN IMPURITY E 95.00%
5MG
$ 501.42

AK Scientific
N',N'-Di(desmethyl)Azithromycin
1mg
$ 151.00

Total 16 raw suppliers

Chemical Property of N',N'-Di(desmethyl) Azithromycin

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:817.289°C at 760 mmHg
PKA:13.28±0.70(Predicted)
Flash Point:448.08°C
Density:1.206g/cm³
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

3’-N,N-Di(desmethyl)Azithromycin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses A metabolite of Azithromycin. A metabolite of Azithromycin. Azithromycin Impurity E

Technology Process of N',N'-Di(desmethyl) Azithromycin

There total 3 articles about N',N'-Di(desmethyl) Azithromycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 172617-84-4
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)‐2‐ethyl‐3,4,10‐trihydroxy‐13‐{(2R,4R,5S,6S)‐5‐hydroxy‐4‐methoxy‐4,6‐dimethyl-tetrahydropyran‐2‐yloxy}‐11‐{(2S,3R,4S,6R)‐3‐hydroxy‐6‐methyl‐4‐methylamino-tetrahydropyran‐2‐yloxy}‐3,5,6,8,10,12,14‐heptamethyl‐1‐oxa‐6‐azacyclopentadecan‐15‐one

: 612069-27-9
3'-N,N-didemethyl-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A

Guidance literature:: With iodine; sodium methylate; In methanol; at 0 - 20 ℃; for 3h;
DOI:10.1016/j.bmcl.2012.03.076

Reference yield:

: 83905-01-5,92470-27-4
Zithromax(R)

: 612069-27-9
3'-N,N-didemethyl-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A

Guidance literature:: Multi-step reaction with 2 steps

1: N-iodo-succinimide / acetonitrile / 1.5 h

2: iodine; sodium methylate / methanol / 3 h / 0 - 20 °C

With N-iodo-succinimide; iodine; sodium methylate; In methanol; acetonitrile;
DOI:10.1016/j.bmcl.2012.03.076