(+-)-6,11-Dimethyl-2,3,8,9-tetramethoxy-11H-indeno(1,2-c)isoquinolinium chloride

Base Information

• Chemical Name: (+-)-6,11-Dimethyl-2,3,8,9-tetramethoxy-11H-indeno(1,2-c)isoquinolinium chloride
• CAS No.: 125455-88-1
• Molecular Formula: C₂₂H₂₄NO₄*Cl
• Molecular Weight: 401.89
• DSSTox Substance ID: DTXSID50925138
• Mol file: 125455-88-1.mol

Synonyms:(+-)-6,11-Dimethyl-2,3,8,9-tetramethoxy-11H-indeno(1,2-c)isoquinolinium chloride;(+-)-5,11-Dimethyl-2,3,8,9-tetramethoxy-11H-indeno(1,2-c)isoquinolinium chloride;11H-Indeno(1,2-c)isoquinolinium, 6,11-dimethyl-2,3,8,9-tetramethoxy-, chloride, (+-)-;125455-88-1;DTXSID50925138;2,3,8,9-tetramethoxy-6,11-dimethyl-11H-indeno[1,2-c]isoquinolin-6-ium chloride;LS-81777

Chemical Property of (+-)-6,11-Dimethyl-2,3,8,9-tetramethoxy-11H-indeno(1,2-c)isoquinolinium chloride

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 401.1393859
• Heavy Atom Count: 28
• Complexity: 517

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C2=CC(=C(C=C2C3=C1C4=CC(=C(C=C4C=[N+]3C)OC)OC)OC)OC.[Cl-]

Technology Process of (+-)-6,11-Dimethyl-2,3,8,9-tetramethoxy-11H-indeno(1,2-c)isoquinolinium chloride

There total 3 articles about (+-)-6,11-Dimethyl-2,3,8,9-tetramethoxy-11H-indeno(1,2-c)isoquinolinium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

5,11-dimethyl-2,3,8,9-tetramethoxy-11H-indeno<1,2-c>isoquinolone (125455-90-5) → 5,11-dimethyl-2,3,8,9-tetramethoxy-11H-indeno<1,2-c>isoquinolinium chloride (125455-88-1)

Guidance literature:

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 8h;

Reference yield:

α-N-methyl-(+/-)-13α-hydroxyxylopinine p-toluenesulfonate (125516-07-6,125516-09-8) → 5,11-dimethyl-2,3,8,9-tetramethoxy-11H-indeno<1,2-c>isoquinolinium chloride (125455-88-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 70 percent / KOH / 2-methyl-propan-2-ol / 60 h / Heating

2: 88 percent / 29percent HCl in EtOH / 0.5 h / Heating

3: 50 percent / 1.) LiAlH₄, 2.) HCl / tetrahydrofuran / 8 h / 0 °C

With hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; In tetrahydrofuran; tert-butyl alcohol;

Reference yield:

3-(2-vinyl-4,5-dimethoxyphenyl)-6,7-dimethoxy-2-methyl-1,2-dihydroisoquinoline-1-one (125455-89-2) → 5,11-dimethyl-2,3,8,9-tetramethoxy-11H-indeno<1,2-c>isoquinolinium chloride (125455-88-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / 29percent HCl in EtOH / 0.5 h / Heating

2: 50 percent / 1.) LiAlH₄, 2.) HCl / tetrahydrofuran / 8 h / 0 °C

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran;

upstream raw materials:

5,11-dimethyl-2,3,8,9-tetramethoxy-11H-indeno<1,2-c>isoquinolone

α-N-methyl-(+/-)-13α-hydroxyxylopinine p-toluenesulfonate

3-(2-vinyl-4,5-dimethoxyphenyl)-6,7-dimethoxy-2-methyl-1,2-dihydroisoquinoline-1-one