tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate

Base Information

Chemical Name:tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate
CAS No.:171559-74-3
Molecular Formula:C₁₁H₁₄N₂O₅
Molecular Weight:254.243
Hs Code.:
European Community (EC) Number:630-668-4
Mol file:171559-74-3.mol

Synonyms:tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate;171559-74-3;TERT-BUTYL 2-(3-NITRO-2-OXOPYRIDIN-1-YL)ACETATE;t-butyl (3-nitro-2-oxo-1,2-dihydropyridyl)acetate;SCHEMBL8993820;DWWAUQIESJGSDR-UHFFFAOYSA-N;MFCD03342947;AKOS037646437;AS-68877;DA-09342;CS-0336872;W18865;t-butyl(3-nitro-2-oxo-1,2-dihydropyridyl)acetate;t-Butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate;tert-butyl (3-nitro-2-oxopyridin-1(2H)-yl)acetate;1,1-Dimethylethyl 3-nitro-2-oxo-1(2H)-pyridineacetate;tert-butyl 2-(3-nitro-2-oxo-1,2-dihydropyridin-1-yl)acetate

Suppliers and Price of tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:254.09027155
Heavy Atom Count:18
Complexity:439

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)CN1C=CC=C(C1=O)[N+](=O)[O-]

Technology Process of tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate

There total 1 articles about tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 23382-09-4,10279-57-9,98759-73-0
silicon dioxide hydrate

: 171559-74-3
tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate

Guidance literature:

Reference yield: 68.0%

: 637-59-2
1-Bromo-3-phenylpropane

: 171559-74-3
tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate

: 179524-57-3
t-butyl [3-nitro-2-oxo-4-(3-phenylpropyl)-1,2,3,4-tetrahydropyridyl]acetate

Guidance literature:: With iodine; magnesium; Zinc chloride; In tetrahydrofuran;

Reference yield:

: 171559-74-3
tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate

: 179524-59-5
t-butyl [3-amino-2-oxo-4-(2-phenylethyl)-1,2-dihydropyridyl]acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) ZnCl₂, 2.) CsCO₃, Pd(OAc)2 / 1.) THF, from 0 deg C to RT, 2.) THF, 50 deg C

2: H₂ / Pd/C / methanol

With palladium diacetate; hydrogen; zinc(II) chloride; palladium on activated charcoal; In methanol;
DOI:10.1016/S0960-894X(99)00102-X