179524-59-5

Basic information

• Product Name: t-butyl [3-amino-2-oxo-4-(2-phenylethyl)-1,2-dihydropyridyl]acetate
• CAS NO: 179524-59-5
• Molecular Weight: 328.411
• Mol File: 179524-59-5.mol

Chemical Properties

• CAS DataBase Reference: t-butyl [3-amino-2-oxo-4-(2-phenylethyl)-1,2-dihydropyridyl]acetate(CAS DataBase Reference)
• NIST Chemistry Reference: t-butyl [3-amino-2-oxo-4-(2-phenylethyl)-1,2-dihydropyridyl]acetate(179524-59-5)
• EPA Substance Registry System: t-butyl [3-amino-2-oxo-4-(2-phenylethyl)-1,2-dihydropyridyl]acetate(179524-59-5)

Safety Data

• Hazardous Substances Data: 179524-59-5(Hazardous Substances Data)

Upstream product

• 226570-06-5 (3-nitro-2-oxo-4-phenethyl-2H-pyridin-1-yl)-acetic acid tert-butyl ester 
• 171559-74-3 tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate 

Downstream Products

• 179526-06-8 [2-oxo-4-phenethyl-3-(trifluoro-ethanesulfonylamino)-2H-pyridin-1-yl]-acetic acid 
• 179526-07-9 (3-benzenesulfonylamino-2-oxo-4-phenethyl-2H-pyridin-1-yl)-acetic acid 
• 179526-08-0 C₁₆H₁₉N₃O₅S 
• 179526-05-7 (3-methanesulfonylamino-2-oxo-4-phenethyl-2H-pyridin-1-yl)-acetic acid 
• 179526-02-4 (3-benzenesulfonylamino-2-oxo-4-phenethyl-2H-pyridin-1-yl)-acetic acid tert-butyl ester 
• 179526-00-2 (3-methanesulfonylamino-2-oxo-4-phenethyl-2H-pyridin-1-yl)-acetic acid tert-butyl ester 
• 179526-03-5 C₂₀H₂₇N₃O₅S 
• 179526-01-3 [2-oxo-4-phenethyl-3-(trifluoro-ethanesulfonylamino)-2H-pyridin-1-yl]-acetic acid tert-butyl ester 

Relevant articles and documents

Aromatic heterocyclic derivatives as enzyme inhibitors

The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.

Aromatic heterocyclic derivatives as enzyme inhibitors

The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.

AROMATIC HETEROCYCLIC DERIVATIVES AS ENZYME INHIBITORS

The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.

Investigation of the S3 site of thrombin: Design, synthesis and biological activity of 4-substituted 3-amino-2-pyridones incorporating P1- argininals

A novel scaffold for P4-P2 dipeptide mimics containing a rigid pyridone spacer was designed based on a virtual library strategy. Several selected nonpeptidic 4-aralkyl or 4-alkylpyridones incorporating a P1- argininal sequence were prepared. The modeling studies, synthesis and biological activities of these unique pyridone derivatives are reported herein.