AKOS BAR-2305

Base Information

• Chemical Name: AKOS BAR-2305
• CAS No.: 869586-30-1
• Molecular Formula: C₁₅H₁₁F₃O₂
• Molecular Weight: 280.246
• Mol file: 869586-30-1.mol

Synonyms:AKOS BAR-2305;(4'-TRIFLUOROMETHYLBIPHENYL-4-YL)ACETIC ACID;4'-(TRIFLUOROMETHYL)-BIPHENYL-3-ACETIC ACID;3-[4-(Trifluoromethyl)phenyl]phenylacetic acid;4-[4-(Trifluoromethyl)phenyl]phenylacetic acid

Chemical Property of AKOS BAR-2305

Chemical Property:

• PSA: 37.30000
• LogP: 3.99950

Purity/Quality:

99% ^*data from raw suppliers

2-(4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-yl)aceticacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of AKOS BAR-2305

There total 2 articles about AKOS BAR-2305 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

3-Bromophenylacetic acid (1878-67-7) + 4-trifluoromethylphenylboronic acid (128796-39-4) → 2-(4’-(trifluoromethyl)-[1,1’-biphenyl]-3-yl)acetic acid (869586-30-1)

Guidance literature:

3-Bromophenylacetic acid; 4-trifluoromethylphenylboronic acid; With sodium carbonate; palladium diacetate; In water; at 120 ℃; for 0.15h; Microwave irradiation;

With hydrogenchloride; In water; pH=2;

Reference yield:

→ 2-(4’-(trifluoromethyl)-[1,1’-biphenyl]-3-yl)acetic acid (869586-30-1)

Guidance literature:

With palladium diacetate; sodium hydrogencarbonate; triphenylphosphine; In 1,4-dioxane; water; at 100 ℃; for 3h;

upstream raw materials:

3-Bromophenylacetic acid

4-trifluoromethylphenylboronic acid