2,6-Dichloro-3-nitrobenzamide

Base Information

• Chemical Name: 2,6-Dichloro-3-nitrobenzamide
• CAS No.: 55775-98-9
• Molecular Formula: C₇H₄Cl₂N₂O₃
• Molecular Weight: 235.026
• DSSTox Substance ID: DTXSID601306950
• Mol file: 55775-98-9.mol

Synonyms:2,6-dichloro-3-nitrobenzamide;55775-98-9;SCHEMBL3886618;WZLQDHBDKJVBRU-UHFFFAOYSA-N;DTXSID601306950;2,6-dichloro-3-nitrobenzoic acid amide

Chemical Property of 2,6-Dichloro-3-nitrobenzamide

Chemical Property:

• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 233.9598974
• Heavy Atom Count: 14
• Complexity: 256

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1[N+](=O)[O-])Cl)C(=O)N)Cl

Technology Process of 2,6-Dichloro-3-nitrobenzamide

There total 3 articles about 2,6-Dichloro-3-nitrobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-dichloro-3-nitrobenzoic acid chloride (151745-47-0) → 2,6-dichloro-3-nitrobenzoic acid amide (55775-98-9)

Guidance literature:

With ammonia; triethylamine; In dichloromethane;

DOI:10.1016/j.bmcl.2006.12.067

Reference yield:

2,6-dichloro-3-nitrobenzoic acid (55775-97-8) → 2,6-dichloro-3-nitrobenzoic acid amide (55775-98-9)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N; NH₃ / CH₂Cl₂

With ammonia; triethylamine; In dichloromethane;

DOI:10.1016/j.bmcl.2006.12.067

Reference yield:

→ 2,6-dichloro-3-nitrobenzoic acid amide (55775-98-9)

Guidance literature:

2,6-Dichlor-benzonitril, 1) Δ, H2SO4/HNO3, 2) konz.wss.NaNO2; neben 2,6-Dichlor-3-nitro-benzoesaeure (I);

upstream raw materials:

2,6-dichloro-3-nitrobenzoic acid chloride

2,6-dichloro-3-nitrobenzoic acid

Downstream raw materials:

3-amino-6-chloro-2-hydroxy-benzamide

6-chloro-3-(2-chloro-3,4-dioxo-cyclobut-1-enylamino)-2-hydroxy-benzamide

6-chloro-2-hydroxy-3-nitrobenzamide