DI(2-Thienyl)-1,1,2,2-tetramethyldisilane

Base Information

• Chemical Name: DI(2-Thienyl)-1,1,2,2-tetramethyldisilane
• CAS No.: 124733-24-0
• Molecular Formula: C12H18S2Si2
• Molecular Weight: 282.57
• Hs Code.: 2934999090
• European Community (EC) Number: 940-959-0
• DSSTox Substance ID: DTXSID90559618
• Nikkaji Number: J1.612.150I
• Wikidata: Q82442384
• Mol file: 124733-24-0.mol

Synonyms:124733-24-0;DI(2-THIENYL)-1,1,2,2-TETRAMETHYLDISILANE;1,1,2,2-tetramethyl-1,2-bis(thiophen-2-yl)disilane;Bis(2-Thienyl)-1,1,2,2-tetramethyldisilane;[dimethyl(thiophen-2-yl)silyl]-dimethyl-thiophen-2-ylsilane;MFCD09266191;1,1,2,2-Tetramethyl-1,2-di(thiophen-2-yl)disilane;1,1,2,2-Tetramethyl-1,2-di(2-thienyl)disilane;Disilane, 1,1,2,2-tetramethyl-1,2-di-2-thienyl-;DTXSID90559618;AKOS025392262;AS-2202;SY347117;CS-0324695;A910011;Di(2-thienyl)-1,1,2,2-tetramethyldisilane, 97per cent

Chemical Property of DI(2-Thienyl)-1,1,2,2-tetramethyldisilane

Chemical Property:

• Melting Point: 42-44℃
• PSA: 56.48000
• LogP: 3.41900
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 282.03884599
• Heavy Atom Count: 16
• Complexity: 227

Purity/Quality:

97% ^*data from raw suppliers

bis(2-Thienyl)-1,1,2,2-tetramethyldisilane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C1=CC=CS1)[Si](C)(C)C2=CC=CS2

Technology Process of DI(2-Thienyl)-1,1,2,2-tetramethyldisilane

There total 1 articles about DI(2-Thienyl)-1,1,2,2-tetramethyldisilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-thienyl chloride (96-43-5) + 1,2-dichlorotetramethylsilane (4342-61-4) → 1,1,2,2-tetramethyl-1,2-di(thiophen-2-yl)disilane (124733-24-0)

Guidance literature:

With magnesium; Yield given. Multistep reaction; 1.) THF, 25 deg C, 3 h, 2.) THF;

DOI:10.1016/0022-328X(89)88003-9

Reference yield: 14.0%

2-phenyl-N-(quinolin-8-yl)-acrylamide (1507347-50-3) + 1,1,2,2-tetramethyl-1,2-di(thiophen-2-yl)disilane (124733-24-0) → (Z)-3-(dimethyl(thiophen-2-yl)silyl)-2-phenyl-N-(quinolin-8-yl)acrylamide

Guidance literature:

With phosphoric acid dibenzyl ester; palladium diacetate; p-benzoquinone; In N,N-dimethyl-formamide; at 80 ℃; for 12h; stereoselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.7b02486

Reference yield:

8-fluoro-3-(2-methylphenoxy)quinoline + 1,1,2,2-tetramethyl-1,2-di(thiophen-2-yl)disilane (124733-24-0) → 3-(2-{[dimethyl(2-thienyl)silyl]methyl}phenoxy)-8-fluoroquinoline

Guidance literature:

8-fluoro-3-(2-methylphenoxy)quinoline; With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; dibenzoyl peroxide; In tetrachloromethane; for 8h; Reflux; Irradiation;

1,1,2,2-tetramethyl-1,2-di(thiophen-2-yl)disilane; With N-ethyl-N,N-diisopropylamine; palladium dichloride; johnphos; In 1-methyl-pyrrolidin-2-one; at 70 ℃; for 3h; Inert atmosphere;

upstream raw materials:

2-thienyl chloride

1,2-dichlorotetramethylsilane

Downstream raw materials:

dimethyl-thiophen-2-yl-silane

dimethyl-bis-(2'-thiophenyl)silane

dimethylmethoxysilane

Methoxy-dimethyl-thiophen-2-yl-silane