Methyl 4-methylpiperidine-2-carboxylate

Base Information

Chemical Name:Methyl 4-methylpiperidine-2-carboxylate
CAS No.:144817-80-1
Molecular Formula:C₈H₁₅NO₂
Molecular Weight:157.213
Hs Code.:
DSSTox Substance ID:DTXSID00573507
Mol file:144817-80-1.mol

Synonyms:144817-80-1;methyl 4-methylpiperidine-2-carboxylate;4-METHYL-PIPERIDINE-2-CARBOXYLIC ACID METHYL ESTER;SCHEMBL7998335;DTXSID00573507;AKOS026726120;SB43097;F8887-3425

Suppliers and Price of Methyl 4-methylpiperidine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Methyl 4-methylpiperidine-2-carboxylate

Chemical Property:

Boiling Point:205.9±33.0 °C(Predicted)
PKA:6.39±0.10(Predicted)
PSA：38.33000
Density:0.982±0.06 g/cm3(Predicted)
LogP:0.87630
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:157.110278721
Heavy Atom Count:11
Complexity:147

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCNC(C1)C(=O)OC

Technology Process of Methyl 4-methylpiperidine-2-carboxylate

There total 2 articles about Methyl 4-methylpiperidine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 4-methyl-piperidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester

: 144817-80-1,184880-03-3,184880-05-5,259538-27-7,339183-93-6
methyl pipecolinate

Guidance literature:: With hydrogenchloride; In ethyl acetate;
DOI:10.1016/S0040-4039(01)00138-1

Reference yield:

: 123387-50-8
4-methylpiperidine-1-carboxylic acid tert-butyl ester

: 144817-80-1,184880-03-3,184880-05-5,259538-27-7,339183-93-6
methyl pipecolinate

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent Turnov_. / sec-BuLi; TMEDA / diethyl ether / 5 h / -90 - 20 °C

2: 100 percent / HCl / ethyl acetate

With hydrogenchloride; N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In diethyl ether; ethyl acetate;
DOI:10.1016/S0040-4039(01)00138-1