3-Bromo Lidocaine

Base Information

• Chemical Name: 3-Bromo Lidocaine
• CAS No.: 1044658-01-6
• Molecular Formula: C14H21BrN2O
• Molecular Weight: 313.238
• Mol file: 1044658-01-6.mol

Synonyms:3-Bromo Lidocaine;N-(3-BroMo-2,6-diMethylphenyl)-2-(diethylaMino)acetaMide

Chemical Property of 3-Bromo Lidocaine

Chemical Property:

• Boiling Point: 389.4±42.0 °C(Predicted)
• PKA: 13.56±0.70(Predicted)
• PSA: 35.83000
• Density: 1.280±0.06 g/cm3(Predicted)
• LogP: 3.99570
• Solubility.: Chloroform, Dichloromethane, Ethyl Acetate, Methanol

Purity/Quality:

98% ^*data from raw suppliers

3-Bromo Lidocaine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Intermediate in the preparation of hydroxylated Lidocaine metabolites.

Technology Process of 3-Bromo Lidocaine

There total 1 articles about 3-Bromo Lidocaine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-diethylamino-N-(2,6-dimethylphenyl)-acetamide (137-58-6) → N-(3-bromo-2,6-dimethyl-phenyl)-2-diethylamine-acetamide (1044658-01-6)

Guidance literature:

With bromine; acetic anhydride; acetic acid; at 20 ℃; for 1h;

Reference yield:

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + N-(3-bromo-2,6-dimethyl-phenyl)-2-diethylamine-acetamide (1044658-01-6) → 2-diethylamine-N-(2,6-dimethyl-3-styryl-phenyl)-acetamide (1044658-47-0)

Guidance literature:

With triphenylphosphine; palladium diacetate; In xylene; at 130 ℃; for 24h;

Reference yield:

N-(3-bromo-2,6-dimethyl-phenyl)-2-diethylamine-acetamide (1044658-01-6) + phenylacetylene (536-74-3) → 2-diethylamine-N-(2,6-dimethyl-3-phenylethynyl-phenyl)-acetamide (1044658-46-9)

Guidance literature:

With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; at 20 ℃;

upstream raw materials:

2-diethylamino-N-(2,6-dimethylphenyl)-acetamide

Downstream raw materials:

2-diethylamine-N-(3-formyl-2,6-dimethyl-phenyl)-acetamide

2-diethylamine-N-(2,6-dimethyl-3-styryl-phenyl)-acetamide

2-diethylamine-N-(2,6-dimethyl-3-phenylethynyl-phenyl)-acetamide

N-(3-benzyloxy-2,6-dimethyl-phenyl)-2-diethylamine-acetamide