1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine

Base Information

Chemical Name:1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine
CAS No.:26662-95-3
Molecular Formula:C₃₉H₇₄NO₈P
Molecular Weight:715.992
Hs Code.:
European Community (EC) Number:634-353-2
UNII:II22JAF28M
DSSTox Substance ID:DTXSID30709973
Wikidata:Q27140321
Metabolomics Workbench ID:15163
Mol file:26662-95-3.mol

Synonyms:26662-95-3;1-Palmitoyl-2-linoleoyl PE;1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine;1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine;II22JAF28M;PE(16:0/18:2(9Z,12Z));PE(16:0/18:2);UNII-II22JAF28M;2-Linoleoyl-1-palmitoyl-sn-glycero-3-phosphatidylethanolamine;Linolein, 1-palmito-2-, 2-aminoethyl hydr;[(2R)-1-[2-aminoethoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] (9Z,12Z)-octadeca-9,12-dienoate;9,12-Octadecadienoic acid (9Z,12Z)-, (1R)-1-((((2-aminoethoxy)hydroxyphosphinyl)oxy)methyl)-2-((1-oxohexadecyl)oxy)ethyl ester;PE 34:2;Ethanol, 2-amino-, dihydrogen phosphate (ester) monoester with 1-palmito-2-linolein, L-;9,12-Octadecadienoic acid (Z,Z)-, 1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester, (R)-;PE(16:1/18:1);16:0-18:2-PE;LMGP02010042;2-Linoleoyl-1-palmitoyl-sn-glycero-3-phosphoethanolamine;SCHEMBL235820;CHEBI:73121;DTXSID30709973;GPEtn(16:0/18:2omega6);PE(16:0/18:2omega6);13206-00-3;AKOS040756040;Phosphatidylethanolamine(16:0/18:2omega6);SR-01000947064;J-016510;SR-01000947064-1;Q27140321;1-hexadecanoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine;(19R)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda(5)-phosphapentacosan-19-yl (9Z,12Z)-octadeca-9,12-dienoate

Suppliers and Price of 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
1-Palmitoyl-2-linoleoyl PE ≥98%
100mg
$ 434.00

Cayman Chemical
1-Palmitoyl-2-linoleoyl PE ≥98%
50mg
$ 248.00

Cayman Chemical
1-Palmitoyl-2-linoleoyl PE ≥98%
10mg
$ 59.00

Cayman Chemical
1-Palmitoyl-2-linoleoyl PE ≥98%
5mg
$ 31.00

Total 4 raw suppliers

Chemical Property of 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine

Chemical Property:

PSA：148.64000
LogP:10.54990
XLogP3:9.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:39
Exact Mass:715.51520532
Heavy Atom Count:49
Complexity:866

Purity/Quality:

98%Min ^*data from raw suppliers

1-Palmitoyl-2-linoleoyl PE ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Lipids -> Ambiguous Lipids
Canonical SMILES:CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCN)OC(=O)CCCCCCCC=CCC=CCCCCC
Isomeric SMILES:CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCN)OC(=O)CCCCCCC/C=C\C/C=C\CCCCC
Uses sn-PLPE is used in the compositions including cationic and neutral lipids for transfecting mRNA into a cell for therapeutic applications for cancer and viral infections.

Technology Process of 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine

There total 13 articles about 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 63-89-8
L-α-Dipalmitoylphosphatidylcholine

: 26662-95-3
1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) phospholipase A₂; 2.) DCC

2: phospholipase D, HCl, CaCl₂ / diethyl ether; H₂O

With hydrogenchloride; phospholipase A₂; dicyclohexyl-carbodiimide; calcium chloride; phospholipase D; In diethyl ether; water;
DOI:10.1021/ja00330a035