[S,(+)]-3-Phenylheptanoic acid

Base Information

• Chemical Name: [S,(+)]-3-Phenylheptanoic acid
• CAS No.: 225917-33-9
• Molecular Formula: C₁₃H₁₉NO
• Molecular Weight: 205.3
• Mol file: 225917-33-9.mol

Synonyms:[S,(+)]-3-Phenylheptanoic acid;[S,(+)]-β-Butylhydrocinnamic acid;(S)-2-Benzylhexanoic acid;[S,(+)]-2-Benzylhexanoic acid

Chemical Property of [S,(+)]-3-Phenylheptanoic acid

Chemical Property:

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [S,(+)]-3-Phenylheptanoic acid

There total 8 articles about [S,(+)]-3-Phenylheptanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

n-butyllithium (109-72-8,29786-93-4) + cinnamamide (621-79-4,22031-64-7) → 2-benzyl-hexanoic acid amide (225917-33-9) + 3-phenyl-heptanoic acid amide

Guidance literature:

With (-)-sparteine; In various solvent(s); at -40 - -20 ℃; for 5h; Yields of byproduct given;

DOI:10.1016/S0040-4039(99)00494-3

Reference yield:

acide 2-benzyl-hexanoique (5668-19-9) → 2-benzyl-hexanoic acid amide (225917-33-9)

Guidance literature:

With thionyl chloride; Behandeln des Saeurechlorids mit wss. Ammoniak;

Reference yield:

2-benzylhexanenitrile (54321-42-5) → 2-benzyl-hexanoic acid amide (225917-33-9)

Guidance literature:

With potassium hydroxide;

upstream raw materials:

2-benzylhexanenitrile

acide 2-benzyl-hexanoique

n-butyllithium

cinnamamide

Refernces