2-Chloro-6-(difluoromethyl)pyridine

Base Information

Chemical Name:2-Chloro-6-(difluoromethyl)pyridine
CAS No.:1026587-36-9
Molecular Formula:C6H4ClF2N
Molecular Weight:163.5524664
Hs Code.:2933399990
European Community (EC) Number:801-602-3
Mol file:1026587-36-9.mol

Synonyms:2-chloro-6-(difluoromethyl)pyridine;1026587-36-9;Pyridine, 2-chloro-6-(difluoromethyl)-;SCHEMBL17667865;TQP0185;MCCFDIGFTIGVNM-UHFFFAOYSA-N;BRB58736;MFCD25368743;AKOS016340212;FH-0717;CS-0156797;D83938;EN300-7259974

Suppliers and Price of 2-Chloro-6-(difluoromethyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-Chloro-6-(difluoromethyl)pyridine
250 mg
$ 480.00

Apolloscientific
2-Chloro-6-(difluoromethyl)pyridine
250mg
$ 300.00

Ambeed
2-Chloro-6-(difluoromethyl)pyridine 97%
1g
$ 435.00

Ambeed
2-Chloro-6-(difluoromethyl)pyridine 97%
250mg
$ 214.00

Ambeed
2-Chloro-6-(difluoromethyl)pyridine 97%
100mg
$ 116.00

Ambeed
2-Chloro-6-(difluoromethyl)pyridine 97%
5g
$ 831.00

Alichem
2-Chloro-6-(difluoromethyl)pyridine
250mg
$ 680.00

Alichem
2-Chloro-6-(difluoromethyl)pyridine
500mg
$ 1078.00

AK Scientific
2-Chloro-6-(difluoromethyl)pyridine
10g
$ 1265.00

Total 7 raw suppliers

Chemical Property of 2-Chloro-6-(difluoromethyl)pyridine

Chemical Property:

PSA：12.89000
LogP:2.67260
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:163.0000331
Heavy Atom Count:10
Complexity:110

Purity/Quality:

98% ,99% , ^*data from raw suppliers

2-Chloro-6-(difluoromethyl)pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC(=C1)Cl)C(F)F

Technology Process of 2-Chloro-6-(difluoromethyl)pyridine

There total 1 articles about 2-Chloro-6-(difluoromethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 54087-03-5
6-chloropyridine-2-carboxaldehyde

: 1026587-36-9
2-chloro-6-(difluoromethyl)pyridine

Guidance literature:: With diethylamino-sulfur trifluoride; In dichloromethane; at -20 - 27 ℃; Inert atmosphere;

Reference yield:

: 1026587-36-9
2-chloro-6-(difluoromethyl)pyridine

: N-((S)-1-(3-(4-chloro-1-methyl-3-(methylsulfonamido)-1H-indazol-7-yl)-4-oxo-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-3-(difluoromethyl)-5,5-difluoro-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c] pyrazol-1-yl)acetamide

: N-((S)-1-((3P)-3-(4-chloro-1-methyl-3-(methylsulfonamido)- 1H-indazol-7-yl)-6-(6-(difluoromethyl)pyridin-2-yl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-3-(difluoromethyl)-5,5-difluoro-3b,4,4a,5- tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide

Guidance literature:: With potassium phosphate; (2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1 ‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl)]palladium(II) methanesulfonate; In 1,4-dioxane; water; at 60 ℃; for 1h; Inert atmosphere;