Methyl 2-(4-(4-chlorophenoxy)phenoxy)propanoate

Base Information

• Chemical Name: Methyl 2-(4-(4-chlorophenoxy)phenoxy)propanoate
• CAS No.: 51337-66-7
• Molecular Formula: C₁₆H₁₅ClO₄
• Molecular Weight: 306.746
• DSSTox Substance ID: DTXSID10965611
• Mol file: 51337-66-7.mol

Synonyms:51337-66-7;Methyl 2-(4-(4-chlorophenoxy)phenoxy)propanoate;methyl 2-[4-(4-chlorophenoxy)phenoxy]propanoate;Propanoic acid, 2-(4-(4-chlorophenoxy)phenoxy)-, methyl ester;Propanoic acid, 2-[4-(4-chlorophenoxy)phenoxy]-, methyl ester;SCHEMBL9320809;DTXSID10965611

Chemical Property of Methyl 2-(4-(4-chlorophenoxy)phenoxy)propanoate

Chemical Property:

• Vapor Pressure: 1.62E-06mmHg at 25°C
• Boiling Point: 397.2°Cat760mmHg
• Flash Point: 149.8°C
• Density: 1.23g/cm³
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 306.0658866
• Heavy Atom Count: 21
• Complexity: 320

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)OC)OC1=CC=C(C=C1)OC2=CC=C(C=C2)Cl

Technology Process of Methyl 2-(4-(4-chlorophenoxy)phenoxy)propanoate

There total 2 articles about Methyl 2-(4-(4-chlorophenoxy)phenoxy)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

→ D-2-[4-(4-chlorophenoxy)-phenoxy]-propionic acid-methyl ester (51337-66-7)

Guidance literature:

Reference yield:

Methyl 2-bromopropionate (5445-17-0) + 4-(4-chlorophenoxy)phenol (21567-18-0) → D-2-[4-(4-chlorophenoxy)-phenoxy]-propionic acid-methyl ester (51337-66-7)

Guidance literature:

With potassium carbonate;

Reference yield:

D-2-[4-(4-chlorophenoxy)-phenoxy]-propionic acid-methyl ester (51337-66-7) → 2-[4-(4-chlorophenoxy)-phenoxy]-1-propanol (57480-08-7)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 1.5h; Heating;

DOI:10.1515/znb-1982-0725

upstream raw materials:

Methyl 2-bromopropionate

4-(4-chlorophenoxy)phenol

Downstream raw materials:

2-[4-(4-chlorophenoxy)-phenoxy]-1-propanol

1-{2-[4-(4-Chloro-phenoxy)-phenoxy]-propyl}-piperidine

Phenyl-carbamic acid 2-[4-(4-chloro-phenoxy)-phenoxy]-propyl ester

(4-Chloro-phenyl)-carbamic acid 2-[4-(4-chloro-phenoxy)-phenoxy]-propyl ester