4-(2-Hydroxymethyl-4-nitro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

Base Information

Chemical Name:4-(2-Hydroxymethyl-4-nitro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester
CAS No.:955369-05-8
Molecular Formula:C16H23N3O5
Molecular Weight:337.376
Hs Code.:
Mol file:955369-05-8.mol

Synonyms:4-(2-Hydroxymethyl-4-nitro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester;tert-butyl 4-(2-(hydroxymethyl)-4-nitrophenyl)piperazine-1-carboxylate

Suppliers and Price of 4-(2-Hydroxymethyl-4-nitro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

A1 Biochem Labs
tert-Butyl4-(2-(hydroxymethyl)-4-nitrophenyl)piperazine-1-carboxylate 95%
1 g
$ 550.00

Matrix Scientific
tert-Butyl 4-(2-(hydroxymethyl)-4-nitrophenyl)piperazine-1-carboxylate 95%
1g
$ 908.00

Matrix Scientific
tert-Butyl 4-(2-(hydroxymethyl)-4-nitrophenyl)piperazine-1-carboxylate 95%
5g
$ 1568.00

Total 1 raw suppliers

Chemical Property of 4-(2-Hydroxymethyl-4-nitro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

Chemical Property:

PSA：98.83000
LogP:2.67030

Purity/Quality:: tert-Butyl4-(2-(hydroxymethyl)-4-nitrophenyl)piperazine-1-carboxylate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(2-Hydroxymethyl-4-nitro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

There total 5 articles about 4-(2-Hydroxymethyl-4-nitro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1017782-93-2
4-(2-formyl-4-nitrophenyl)piperazine-1-carboxylic acid tert-butyl ester

: 955369-05-8
4-(2-(hydroxymethyl)-4-nitrophenyl)piperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1021/jm200326p

Reference yield:

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 955369-05-8
4-(2-(hydroxymethyl)-4-nitrophenyl)piperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 90 °C

2: sodium tetrahydroborate / tetrahydrofuran / 0 - 20 °C

With sodium tetrahydroborate; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm200326p

Reference yield:

: 27996-87-8
2-fluoro-5-nitrobenzaldehye

: 955369-05-8
4-(2-(hydroxymethyl)-4-nitrophenyl)piperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / dimethyl sulfoxide / 32 h / 95 °C

2: sodium tetrahydroborate / ethanol / 3 h / 20 °C

With sodium tetrahydroborate; potassium carbonate; In ethanol; dimethyl sulfoxide;