6β-Hydroxy Norgestrel

Base Information

Chemical Name:6β-Hydroxy Norgestrel
CAS No.:55555-97-0
Molecular Formula:C₂₁H₂₈O₃
Molecular Weight:328.452
Hs Code.:
Mol file:55555-97-0.mol

Synonyms:6β-Hydroxy Norgestrel

Suppliers and Price of 6β-Hydroxy Norgestrel

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6β-Hydroxylevonorgestrel
10mg
$ 145.00

Total 11 raw suppliers

Chemical Property of 6β-Hydroxy Norgestrel

Chemical Property:

Melting Point:200-202 °C
Boiling Point:504.1±50.0 °C(Predicted)
PKA:13.03±0.60(Predicted)
PSA：57.53000
Density:1.20±0.1 g/cm3(Predicted)
LogP:2.85340
Storage Temp.:Refrigerator, Under Inert Atmosphere
Solubility.:Chloroform (Soluble, Sonicated), DMSO (Slightly, Sonicated), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

6β-Hydroxylevonorgestrel ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses A hydroxylated impurity of Norgestrel 6β-Hydroxylevonorgestrel is an impurity from the synthesis of Levonorgestrel (N689510), an oral contraceptive. 6β-Hydroxylevonorgestrel (Levonorgestrel EP Impurity H) is an impurity from the synthesis of Levonorgestrel (N689510), an oral contraceptive.

Technology Process of 6β-Hydroxy Norgestrel

There total 3 articles about 6β-Hydroxy Norgestrel which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 797-63-7
levonorgestrel

: 13β-ethyl-17α-ethynyl-10,17β-dihydroxy-4,6-dien-3-one

: 13β-ethyl-17α-ethynyl-10β,17β-dihydroxy-4-en-3-one

: 55555-97-0
13β-ethyl-17α-ethynyl-6β,17β-dihydroxy-4-en-3-one

Guidance literature:: With cunninghamella blakesleea; In methanol; Microbiological reaction;
DOI:10.1080/14786419.2019.1655018

Reference yield:

: 797-63-7
levonorgestrel

: 87585-03-3
(6S,8R,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-6,17-dihydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

: 55555-97-0
13β-ethyl-17α-ethynyl-6β,17β-dihydroxy-4-en-3-one

Guidance literature:: at 37 ℃; for 0.166667h; in incubation mixture, with rat liver microsomes; or perbenzoic acid oxidation of dienol acetate;
DOI:10.1016/S0040-4039(01)91156-6