Estradiol 3-sulfamate

Base Information

Chemical Name:Estradiol 3-sulfamate
CAS No.:172377-52-5
Molecular Formula:
Molecular Weight:0
Hs Code.:
European Community (EC) Number:658-092-9
UNII:WO55ODW08Z
DSSTox Substance ID:DTXSID801337121
Nikkaji Number:J697.656E
Wikipedia:Estradiol_sulfamate
Wikidata:Q76393589
Pharos Ligand ID:7XRH49UA2K2Z
Metabolomics Workbench ID:149850
ChEMBL ID:CHEMBL219321

Synonyms:E2MATE cpd;estradiol-3-O-sulfamate

Suppliers and Price of Estradiol 3-sulfamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Estradiol 3-sulfamate

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:351.15042945
Heavy Atom Count:24
Complexity:588

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)OS(=O)(=O)N
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)OS(=O)(=O)N
Recent ClinicalTrials:PGL2001 Proof of Concept Study in Symptomatic Endometriosis
Recent EU Clinical Trials:A Phase II, Multicentre, Randomised, Two-Arm, Parallel Group, Double-Blind, Placebo controlled Study of the Steroid Sulfatase Inhibitor PGL2001 with concomitant administration of NETA (norethisterone acetate) for the treatment of symptoms related to endometriosis

Technology Process of Estradiol 3-sulfamate

There total 12 articles about Estradiol 3-sulfamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.1%