4-Bromo-5-((4-hydroxyphenethylamino)methyl)-2-methoxyphenol

Base Information

Chemical Name:4-Bromo-5-((4-hydroxyphenethylamino)methyl)-2-methoxyphenol
CAS No.:179107-93-8
Molecular Formula:C16H18BrNO3
Molecular Weight:352.228
Hs Code.:
DSSTox Substance ID:DTXSID70429441
Mol file:179107-93-8.mol

Synonyms:179107-93-8;4-bromo-5-((4-hydroxyphenethylamino)methyl)-2-methoxyphenol;PHENOL, 4-BROMO-5-[[[2-(4-HYDROXYPHENYL)ETHYL]AMINO]METHYL]-2-METHOXY-;4-bromo-5-[[2-(4-hydroxyphenyl)ethylamino]methyl]-2-methoxyphenol;4-bromo-5-(((4-hydroxyphenethyl)amino)methyl)-2-methoxyphenol;SCHEMBL7714778;DTXSID70429441;JBFKJIRYXUAQSW-UHFFFAOYSA-N;CS-M0845;AKOS037650134;CS-14336;4-Bromo-5-({[2-(4-hydroxyphenyl)ethyl]amino}methyl)-2-methoxyphenol

Suppliers and Price of 4-Bromo-5-((4-hydroxyphenethylamino)methyl)-2-methoxyphenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of 4-Bromo-5-((4-hydroxyphenethylamino)methyl)-2-methoxyphenol

Chemical Property:

Boiling Point:503.3±45.0 °C(Predicted)
PKA:8.88±0.23(Predicted)
PSA：61.72000
Density:1.435±0.06 g/cm3(Predicted)
LogP:3.59210
XLogP3:3.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:351.04701
Heavy Atom Count:21
Complexity:297

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C(=C1)Br)CNCCC2=CC=C(C=C2)O)O
Uses 4-Bromo-5-[[[2-(4-hydroxyphenyl)ethyl]amino]methyl]-2-methoxyphenol is used in preparation of racemic Galanthamine with Bromomethylmethoxybromophenol and Tyramine via K3[Fe(CN)6] initiated ring closing.

Technology Process of 4-Bromo-5-((4-hydroxyphenethylamino)methyl)-2-methoxyphenol

There total 7 articles about 4-Bromo-5-((4-hydroxyphenethylamino)methyl)-2-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 51-67-2
tyrosamine

: 2973-59-3
2-bromoisovanillin

: 179107-93-8
N-(p-hydroxyphenylethyl)-N-(6-bromo-3-hydroxy-4-methoxybenzyl)amine

Guidance literature:: tyrosamine; 2-bromoisovanillin; In methanol; at 25 ℃; for 2h;

With methanol; sodium tetrahydroborate; at 0 - 25 ℃; for 3h;
DOI:10.1039/d0ra00935k