(R)-1-methyl-5-oxopyrrolidine-2-carboxylic acid

Base Information

Chemical Name:(R)-1-methyl-5-oxopyrrolidine-2-carboxylic acid
CAS No.:952345-00-5
Molecular Formula:C₆H₉NO₃
Molecular Weight:143.142
Hs Code.:
European Community (EC) Number:821-936-3
Nikkaji Number:J291.361E
Wikidata:Q76415234
Mol file:952345-00-5.mol

Synonyms:952345-00-5;(R)-1-methyl-5-oxopyrrolidine-2-carboxylic acid;1-methyl-5-oxo-D-Proline;D-Proline, 1-methyl-5-oxo-;(2R)-1-Methyl-5-oxopyrrolidine-2-carboxylic acid;SCHEMBL1587617;AMY16226;CNB34500;MFCD26937700;DS-20042;CS-0044233;EN300-343787;F14371;(R)-1-methyl-5-oxopyrrolidine-2-carboxylicacid;A928217

Suppliers and Price of (R)-1-methyl-5-oxopyrrolidine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-1-Methyl-5-oxopyrrolidine-2-carboxylicacid 97%
1g
$ 151.00

Chemenu
(R)-1-Methyl-5-oxopyrrolidine-2-carboxylicacid 97%
1g
$ 327.00

Ambeed
(R)-1-Methyl-5-oxopyrrolidine-2-carboxylicacid 97%
1g
$ 92.00

Ambeed
(R)-1-Methyl-5-oxopyrrolidine-2-carboxylicacid 97%
250mg
$ 47.00

Ambeed
(R)-1-Methyl-5-oxopyrrolidine-2-carboxylicacid 97%
100mg
$ 28.00

Alichem
(R)-1-Methyl-5-oxopyrrolidine-2-carboxylicacid
1g
$ 343.00

Alichem
(R)-1-Methyl-5-oxopyrrolidine-2-carboxylicacid
250mg
$ 152.60

AK Scientific
(R)-1-Methyl-5-oxopyrrolidine-2-carboxylicacid
1g
$ 196.00

Acrotein
1-Methyl-5-oxo-D-proline 97%
1g
$ 174.20

AccelPharmtech
1-methyl-5-oxo-D-Proline 97%
1G
$ 190.00

Total 7 raw suppliers

Chemical Property of (R)-1-methyl-5-oxopyrrolidine-2-carboxylic acid

Chemical Property:

Boiling Point:361.7±35.0 °C(Predicted)
PKA:3.53±0.20(Predicted)
PSA：57.61000
Density:1.319±0.06 g/cm3(Predicted)
LogP:-0.37030
Storage Temp.:2-8°C
XLogP3:-0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:143.058243149
Heavy Atom Count:10
Complexity:178

Purity/Quality:

97% ^*data from raw suppliers

(R)-1-Methyl-5-oxopyrrolidine-2-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C(CCC1=O)C(=O)O
Isomeric SMILES:CN1[C@H](CCC1=O)C(=O)O

Technology Process of (R)-1-methyl-5-oxopyrrolidine-2-carboxylic acid

There total 23 articles about (R)-1-methyl-5-oxopyrrolidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 146963-42-0
N-methyl-L-2-oxopyrrolidine-5-carboxylic acid benzyl ester

: 52574-06-8,952345-00-5
(2S)-1-methyl-5-oxopyrrolidine-2-carboxylic acid

Guidance literature:: With hydrogen; palladium; In methanol;
DOI:10.1021/jo00058a049

Reference yield: 71.0%

: 591225-53-5
tert-butyl (2S)-1-methyl-5-oxopyrrolidine-2-carboxylate

: 52574-06-8,952345-00-5
(2S)-1-methyl-5-oxopyrrolidine-2-carboxylic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h;
DOI:10.1016/S0040-4020(03)00420-4

Reference yield:

: 108645-70-1,177314-35-1
ethyl 1-methyl-5-oxopyrrolidine-2-carboxylate

: 72442-37-6,952345-00-5
1-methyl-5-oxopyrrolidine-2-carboxylic acid

Guidance literature:: ethyl 1-methyl-5-oxopyrrolidine-2-carboxylate; With sodium hydroxide; water; In ethanol; isopropyl alcohol; at 0 ℃; for 4h;

With hydrogenchloride; In water; pH=1; Product distribution / selectivity;