Dimethyl glutamic acid

Base Information

• Chemical Name: Dimethyl glutamic acid
• CAS No.: 6312-54-5
• Molecular Formula: C7H13 N O4
• Molecular Weight: 175.185
• UNII: 2E8WP6L8DL
• DSSTox Substance ID: DTXSID401021566
• Nikkaji Number: J3.445.975D
• Wikidata: Q27254619
• Mol file: 6312-54-5.mol

Synonyms:Dimethyl glutamic acid;n,n-dimethylglutamic acid;2E8WP6L8DL;L-Glutamic acid, N,N-dimethyl-;Glutamic acid, N,N-dimethyl-, L-;NSC-40352;UNII-2E8WP6L8DL;6312-54-5;dimethylglutamic acid;SCHEMBL198528;JCHFXGIXHDRBFU-YFKPBYRVSA-N;DTXSID401021566;DIMETHYL GLUTAMIC ACID [INCI];(S)-2-(dimethylamino)pentanedioic acid;(2S)-2-(dimethylamino)pentanedioic acid;EN300-7844608;Q27254619

Chemical Property of Dimethyl glutamic acid

Chemical Property:

• Vapor Pressure: 0.000114mmHg at 25°C
• Boiling Point: 312.7°C at 760 mmHg
• Flash Point: 142.9°C
• PSA: 77.84000
• Density: 1.242g/cm³
• LogP: -0.13400
• XLogP3: -2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 175.08445790
• Heavy Atom Count: 12
• Complexity: 178

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C(CCC(=O)O)C(=O)O
• Isomeric SMILES: CN(C)[C@@H](CCC(=O)O)C(=O)O

Technology Process of Dimethyl glutamic acid

There total 1 articles about Dimethyl glutamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + L-glutamic acid (56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) → N,N-dimethyl-(L)-glutamic acid (6312-54-5)

Guidance literature:

With hydrogen; palladium on activated charcoal; In water; at 48 ℃;

DOI:10.1039/b208325f

Reference yield:

N,N-dimethyl-(L)-glutamic acid (6312-54-5) → 1,5-pentanedioic acid (110-94-1) + 2-hydroxyglutaric acid (2889-31-8,636-67-9) + 1-methyl-5-oxopyrrolidine-2-carboxylic acid (72442-37-6,952345-00-5)

Guidance literature:

With platinum on carbon; hydrogen; In water; at 200 ℃; for 24h; under 22502.3 Torr; Reagent/catalyst; Green chemistry;

DOI:10.1039/c6gc03222b

Reference yield:

methanol (67-56-1) + N,N-dimethyl-(L)-glutamic acid (6312-54-5) → Dimethyl glutarate (1119-40-0) + 1,5-dimethyl 2-methoxypentanedioate (178888-44-3)

Guidance literature:

With 5 wt% Pt/TiO2; hydrogen; at 240 ℃; for 24h; under 22502.3 Torr; Reagent/catalyst; Temperature; Pressure; Time; Catalytic behavior; Green chemistry;

DOI:10.1039/c6gc03222b

upstream raw materials:

formaldehyd

L-glutamic acid

Downstream raw materials:

1,5-pentanedioic acid

2-hydroxyglutaric acid

1-methyl-5-oxopyrrolidine-2-carboxylic acid

(+/-)-tetrahydro-5-oxo-2-furancarboxylic acid methyl ester